Executive Medical Director, Clinical Development

Role Summary

Executive Medical Director, Clinical Development-Oncology. Lead execution of key bispecific antibody programs in solid tumors, driving program strategy and scientific/medical rigor across functions from early development through late-phase/registrational trials. Hybrid role with on-site requirement; based in San Diego or Pasadena, CA.

Responsibilities

• Provides strategic leadership and medical expertise for clinical development of bispecific antibodies in oncology
• Drives program strategy for complex individual and combination programs, delivering comprehensive Development Plans
• Defines global clinical development strategies, anticipating regulatory pathways, competitive dynamics, and scientific inflection points
• Partners with Biostatistics, Regulatory Affairs, Clinical Operations, Safety, Translational Science, and other functions to ensure cohesive program execution
• Drives integrated decision-making by aligning stakeholders
• Designs, plans, and oversees the execution of clinical studies from early through late-stage development
• Works with Clinical Operations to provide medical expertise and execute trials on time and with high quality
• Coordinates ongoing review of clinical data, data analyses, and data interpretation; supports data cleaning and interpretation
• Partners with Pharmacovigilance to provide internal safety monitoring for trials
• Delivers clinical protocols and key clinical elements of documents including investigator brochures, DSURs, IND modules, and regulatory correspondence
• Develops and maintains relationships with key opinion leaders and trial investigators
• Represent the company as a senior clinical leader in scientific, regulatory, and medical forums
• Ensure compliance with regulatory standards and guidelines; adhere to department and company policies
• Provide oversight, mentorship, and direction to direct and indirect reports
• Perform other duties as required

Qualifications

• Medical degree (MD, DO or equivalent), board certification in hematology and/or oncology
• Minimum 8 years of directly relevant pharmaceutical industry experience in clinical development, with at least 5 years in oncology/immune-oncology
• Experience including data review, safety monitoring, protocol development, data analyses, interpretation, and publications
• Experience working on cross-functional clinical trial teams and liaising with investigators
• Prior people management experience
• The company may consider internal experience in lieu of some education or experience requirements

Skills

• Strong initiative, organization, and attention to detail
• Excellent written and oral communication and interpersonal skills
• Ability to deliver concise, high-quality executive presentations
• Ability to manage others through coaching and supervision
• Ability to build effective cross-disciplinary relationships and manage multiple projects under pressure
• Strong analytical, assessment, and problem-solving skills
• Ability to analyze and interpret complex clinical data
• Expertise in data review, safety monitoring, protocol development, data analyses, and publications; experience with cross-functional clinical trial teams
• Experience across the full study life cycle; monoclonal antibody/immunotherapy clinical development and translational medicine/early-phase trials preferred

Education

• Medical degree required; board certification in hematology and/or oncology

Additional Requirements

• Occasional travel may be required, including travel between Pasadena and San Diego offices
• Full-time on-site work; hybrid option with minimum 2 days on-site per week