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Executive Director, Research Oncology

Amgen
August 28, 2026
Full-time
Remote friendly (South San Francisco, CA)
Worldwide
Clinical Research and Development
Role: Executive Director, Oncology Research leading Amgen's efforts in discovering and developing novel therapeutics for solid tumors and hematologic malignancies. Responsibilities include shaping research strategy, leading preclinical and translational programs (initially focusing on ADCs and expanding to other modalities), managing high-performing teams, and fostering external collaborations. The role involves integrating data science, AI/ML, and biomarker insights, supporting clinical translation, and guiding cross-functional partnerships. Qualifications: Doctorate in Cancer Biology or related field with 6+ years (or equivalent experience) in oncology research; 15+ years preferred with proven leadership in early drug discovery, IND/CTA submission, and external partnerships. Skills: expertise in cell signaling, tumor genetics, mechanisms of response/resistance, biotherapeutics, and data integration; strong communication and leadership skills. High-Value: Focus on oncology, ADCs, preclinical to clinical transition, external collaborations, and AI/ML applications. Work setup: Not specified, but implied to involve leadership in a fast-paced, matrixed environment with strategic influence.