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Executive Director, Program and Portfolio Management

MacroGenics, Inc.
August 17, 2026
Full-time
Remote friendly (Rockville, MD)
Worldwide
Operations
Role: Senior leadership position overseeing macro-level strategic planning and execution of biopharma development portfolios, primarily in oncology or biologics. Responsibilities: lead cross-functional teams managing pipeline assets from discovery through clinical development, regulatory approval, and commercialization; develop and align comprehensive plans covering strategy, timelines, budgets, risks, and decision points; enhance portfolio governance, facilitate high-quality decision-making, and support disciplined execution; manage external partnerships and ensure transparency and accountability within program teams. Requirements: Bachelor's in life sciences, with an advanced degree (MS, PhD, PharmD, MD) preferred; 12+ years in biotech/pharma, including 7+ years of people management and experience in drug development, portfolio management, or product leadership; proven success in managing complex, multi-phase development programs; experience with oncology or biologics is a plus. High-Value: expertise in drug discovery, clinical development, regulatory strategies, CMC, and commercialization in biologics or immunology; familiarity with external partner management, portfolio governance, and cross-functional leadership. Work Setup: Not specified; likely in a senior leadership capacity supporting strategic initiatives.