Executive Director, Portfolio & Program Management
Vertex Pharmaceuticals
October 2, 2026
Full-time
Remote friendly (Boston, MA)
Worldwide
Operations
Role: Executive Director of Portfolio & Program Management, leading global efforts across drug development and commercialization for multiple disease areas at Vertex. Responsibilities include providing strategic and operational leadership to cross-functional teams, mentoring senior program managers, driving resource optimization and organizational design, and representing the portfolio on governance and senior leadership forums. The role ensures integration of research, development, and commercialization aligned with Disease Area Strategy Teams (DST). Requirements: Bachelor's in Life Sciences or related field, 15+ years of experience including 7+ years in management of large, complex teams and programs, with deep expertise in portfolio management, strategic planning, risk/resource management, and drug discovery/development. Skills needed include leadership of diverse teams, financial acumen, stakeholder collaboration, and biopharma knowledge across disciplines. High-value specifics: experience in managing multiple disease areas, strategic growth initiatives, and operational excellence within a global biotech setting. The position is hybrid, based in Boston (Seaport), with flexible remote work options and no explicit travel requirements.