Executive Director, Portfolio Lead, Global Discovery Chemistry

Role Summary

The Portfolio Lead/Executive Director, Global Discovery Chemistry (GDC) leads strategy, integration, and execution of chemistry programs across one or more therapeutic areas. As a member of the GDC Leadership Team, this role shapes the overall discovery chemistry strategy at Bristol Myers Squibb and oversees matrix and direct-report teams to identify, prioritize, and develop innovative drug molecules while meeting rigorous scientific standards and aligning with portfolio objectives. The role collaborates with functional leaders across Research and Development to guide molecular invention, manage resources, and leverage technology to maximize the value of the global discovery chemistry pipeline. The candidate must demonstrate a vision for scientific excellence, a collaborative mindset, and the ability to inspire teams to achieve ambitious goals in a dynamic environment.

Responsibilities

• Provide strategic leadership and oversee the portfolio delivery of multiple discovery chemistry programs, ensuring they are aligned with organizational objectives and consistently produce high-quality, differentiated small molecule drugs.
• Manage site operations for Global Discovery Chemistry team at the Lawrenceville, NJ location, upholding organizational standards and ensuring that scientific initiatives are carried out efficiently. This includes promoting a productive work environment and supporting local teams in meeting strategic goals.
• Act as a mentor to leaders, teams, and scientists within the organization, encouraging the adoption and implementation of AI/ML tools and other innovative technologies that accelerate the development of new medicines.
• Promote collaboration and accountability within both matrix and line teams to ensure the delivery of impactful scientific results.
• Ensure strategic alignment and progress across one or more therapeutic areas within the BMS portfolio.

Qualifications

• A Ph.D. in organic or medicinal chemistry with a minimum of 15 years of relevant post-graduate experience in the pharmaceutical or biotechnology sectors.
• Demonstrated success in leading medicinal chemistry teams that have advanced innovative drug candidates to clinical development. Experience with one or more chemical modalities such as antibody-drug conjugates (ADCs), monovalent or bivalent protein degraders, oligonucleotides, and/or macrocyclic peptides is preferred.
• Proven ability to drive scientific excellence and inspire cross-functional teams to achieve ambitious objectives.
• Experience working collaboratively with diverse stakeholders in complex research and development environments.
• Strong leadership and communication skills, combined with a collaborative and forward-thinking approach.