Executive Director Clinical Development Lead- Myasthenias Gravis

Role Summary

The Executive Director, Clinical Development Lead is responsible for driving the strategic and operational leadership of clinical development programs within Vor Bio. Reporting to the Chief Medical Officer, this role ensures the successful design, execution, and delivery of clinical trials, supporting the advancement of innovative therapies from late-stage development through regulatory approval. The Executive Director will collaborate cross-functionally to shape clinical strategy, manage teams, and represent clinical development both internally and externally.

Responsibilities

• Strategic Leadership:
  • Develop and implement clinical development strategies for assigned programs, aligning with corporate objectives and regulatory requirements.
  • Lead the planning and execution of clinical trials, ensuring scientific rigor and operational excellence.
• Program Oversight:
  • Oversee late phase clinical development, from protocol design to study completion and data analysis.
  • Manage timelines, budgets, and resources to ensure efficient program delivery.
• Cross-Functional Collaboration:
  • Partner with Clinical Operations, Regulatory Affairs, Medical Affairs, Biostatistics, Data Management, and other key stakeholders to ensure integrated program execution.
  • Facilitate communication between internal teams and external partners, including CROs, investigators, and regulatory agencies.
• Team Leadership:
  • Build, mentor, and lead high-performing clinical development teams.
  • Foster a culture of innovation, accountability, and continuous improvement.
• Regulatory & Compliance:
  • Ensure all clinical activities comply with GCP, ICH guidelines, and applicable regulations.
  • Prepare and present clinical data and program updates to regulatory authorities and advisory boards.
• Stakeholder Engagement:
  • Represent Vor Bio at scientific conferences, advisory meetings, and industry forums.
  • Engage with key opinion leaders and external experts to inform clinical strategy.

Qualifications

• Education:
  • MD (or MD/PhD) with experience in neuromuscular disease and/or immunology drug development.
• Experience:
  • Minimum of 10+ years in clinical development within the pharmaceutical or biotechnology industry.
  • Proven track record of leading successful clinical programs and cross-functional teams.
  • Experience with regulatory submissions and interactions.
• Skills & Competencies:
  • Strong strategic thinking and problem-solving abilities.
  • Excellent communication, presentation, and interpersonal skills.
  • Ability to manage multiple priorities in a fast-paced environment.
  • Demonstrated leadership and team-building capabilities.