Executive Director, Biostatistics

General Summary:
The Executive Director of Biostatistics is a strategic, dynamic, and empowered leader overseeing statistical functions in support of multiple therapeutic areas or portfolios. Responsibilities include methodological and quantitative scientific contributions while driving operational excellence, partnering across R&D to generate evidence supporting Vertex pipelines/products.

Key Duties And Responsibilities:
- Lead/driving scientific statistical methodological expertise using best-in-class and novel statistical approaches to impact the portfolio.
- Serve as subject matter expert and owner for key biometrics processes and operating models related to Biostatistics SOPs, process maps, training, and software/tools.
- Own statistical support in therapeutic areas and/or Global Medical Affairs (early/late development, post-marketing studies, RWE studies, and analyses supporting reimbursement).
- Drive innovative trial designs to improve trial efficiency and shape executive views.
- Serve as a key leader on the Biostatistics Leadership Team for data operations, statistics, and statistical reporting/analytics.
- Represent Vertex externally in industry, academic, and regulatory forums.

Knowledge And Skills:
- Outstanding communication (scientific/technical/process writing, influential speech/negotiation, explaining complex concepts, executive-level scientific discourse).
- Experience developing and leading high-performing teams.
- Expert in statistical methodology (best practices and industry trends); agile learner/change agent.
- Executive presence and emotional intelligence.

Education And Experience:
- M.S. or Ph.D. in Statistics or Biostatistics.
- 15 years of relevant work experience (or equivalent combination of education and experience).