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Enterprise Programs - Senior Program Manager

Amgen
Full-time
Remote friendly (United States)
United States
IT

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Role Summary

Lead strategic, business-driven technology initiatives across a global, matrixed organization to deliver measurable business value. Oversee a portfolio of transformational programs that enable innovation, improve operational efficiency, and advance data-driven decision making. Collaborate with cross-functional teams and external partners to align technology delivery with business priorities and drive adoption.

Responsibilities

  • Lead delivery of complex programs that align to enterprise goals and deliver measurable value
  • Drive transformational programs to deliver on business priorities
  • Work closely with business stakeholders to define outcomes, ensure solutions are implemented as planned and drive adoption
  • Translate business needs into executable program plans, including scope, timelines, resource planning, and budget oversight
  • Partner with cross-functional teams including data & analytics, enterprise applications, and digital product teams to deliver outcomes
  • Manage program governance, steering committees, and status reporting for senior partners
  • Drive structured methodologies such as Agile, SAFe, or hybrid approaches to improve delivery efficiency and responsiveness
  • Track program KPIs, ROI, and performance metrics aligned to business success criteria
  • Coordinate organizational change, business readiness, and stakeholder engagement activities across functions and geographies
  • Build trust and alignment across technology teams and business leaders to sustain long-term strategic partnerships
  • Apply continuous improvement practices to program execution and delivery frameworks

Qualifications

  • Required: Doctorate degree and 2 years of Scientific and/or IT Operations and/or Business experience
  • Required: Master’s degree and 4 years of Scientific and/or IT Operations and/or Business experience
  • Required: Bachelor’s degree and 6 years of Scientific and/or IT Operations and/or Business experience
  • Required: Associate’s degree and 10 years of Scientific and/or IT Operations and/or Business experience
  • Required: High school diploma / GED and 12 years of Scientific and/or IT Operations and/or Business experience
  • Preferred: 6–10 years of experience delivering business technology solutions and programs in a matrixed, global organization
  • Preferred: Demonstrated success in aligning technology execution with business strategy to achieve measurable outcomes
  • Preferred: Experience leading transformational programs or M&As
  • Preferred: Experience leading programs involving business process optimization, digital product rollouts, enterprise applications, or analytics platforms
  • Preferred: Proficiency with program and portfolio management tools (e.g., Smartsheet, JIRA, ServiceNow, Confluence) and executive reporting dashboards
  • Preferred: Strong stakeholder engagement, communication, and change leadership skills across business and technical audiences
  • Preferred: Ability to manage vendor relationships and third-party service providers in a co-delivery model
  • Preferred: Familiarity with data privacy, GxP, and regulatory compliance frameworks in a life sciences context
  • Preferred: PMP, SAFe, Agile, or Lean certification

Education

  • Doctorate degree and 2 years of Scientific and/or IT Operations and/or Business experience
  • Master’s degree and 4 years of Scientific and/or IT Operations and/or Business experience
  • Bachelor’s degree and 6 years of Scientific and/or IT Operations and/or Business experience
  • Associate’s degree and 10 years of Scientific and/or IT Operations and/or Business experience
  • High school diploma / GED and 12 years of Scientific and/or IT Operations and/or Business experience