Distinguished Scientist, Transgenic Model and Technology
Sanofi
August 08, 2026
Remote friendly (Cambridge, MA)
United States
$178,500 - $257,833.33 USD yearly
Clinical Research and Development
Responsibilities
- Lead global Transgenic Model & Technology (TMT) work: advance genome engineering and mouse genetics for in vivo model development.
- Use transgenesis and CRISPR technologies to design and execute experiments for target validation, proof-of-concept, and efficacy.
- Identify and implement new transgenesis/genome engineering technologies (CRISPR/Cas systems, base/prime editing).
- Advise research programs on in vivo and preclinical study design; integrate AI/digital tools for model design and data analysis.
- Provide strategic leadership aligning transgenic capabilities to research priorities; coordinate transversal teams across divisions/sites/partners.
- Establish project management frameworks; manage relationships with model providers/CROs/academics; negotiate licenses/contracts; maintain quality standards.
- Supervise/mentor staff; participate in hiring, performance, and development.
Qualifications/Requirements
- Ph.D. in Molecular Biology, Genetics, Developmental Biology, or related.
- Extensive postdoctoral/industry experience in mouse molecular genetics and transgenic model development.
- Proven scientific leadership in academic or pharma/biotech settings.
- Minimum 5 years hands-on experience in this role.
Preferred/Additional Skills
- Deep expertise creating transgenic models using CRISPR/Cas9, Cas12, base editors, prime editors.
- Strong foundation in molecular biology, mouse genetics, embryology, and reproductive technologies.
- Experience across immunology, oncology, rare diseases, neuroscience.
- Strategic thinking; AI/digital familiarity; strong PM, contract/vendor, budgeting, communication; works in matrix orgs.
Benefits
- Competitive compensation and comprehensive benefits; flexible work arrangements; professional development.
- At least 14 weeks’ gender-neutral parental leave.
Application instructions
- Not provided.
- Lead global Transgenic Model & Technology (TMT) work: advance genome engineering and mouse genetics for in vivo model development.
- Use transgenesis and CRISPR technologies to design and execute experiments for target validation, proof-of-concept, and efficacy.
- Identify and implement new transgenesis/genome engineering technologies (CRISPR/Cas systems, base/prime editing).
- Advise research programs on in vivo and preclinical study design; integrate AI/digital tools for model design and data analysis.
- Provide strategic leadership aligning transgenic capabilities to research priorities; coordinate transversal teams across divisions/sites/partners.
- Establish project management frameworks; manage relationships with model providers/CROs/academics; negotiate licenses/contracts; maintain quality standards.
- Supervise/mentor staff; participate in hiring, performance, and development.
Qualifications/Requirements
- Ph.D. in Molecular Biology, Genetics, Developmental Biology, or related.
- Extensive postdoctoral/industry experience in mouse molecular genetics and transgenic model development.
- Proven scientific leadership in academic or pharma/biotech settings.
- Minimum 5 years hands-on experience in this role.
Preferred/Additional Skills
- Deep expertise creating transgenic models using CRISPR/Cas9, Cas12, base editors, prime editors.
- Strong foundation in molecular biology, mouse genetics, embryology, and reproductive technologies.
- Experience across immunology, oncology, rare diseases, neuroscience.
- Strategic thinking; AI/digital familiarity; strong PM, contract/vendor, budgeting, communication; works in matrix orgs.
Benefits
- Competitive compensation and comprehensive benefits; flexible work arrangements; professional development.
- At least 14 weeks’ gender-neutral parental leave.
Application instructions
- Not provided.