Discovery ADME Project Leader (Radioligand Therapeutics)

Role: Discovery ADME Project Leader specializing in Radioligand Therapeutics (Radioconjugates), responsible for integrating ADME strategies with drug discovery efforts to optimize candidate profiles. Core responsibilities: develop and implement preclinical ADME plans aligned with discovery targets, interpret PK, metabolism, and off-target liabilities to de-risk programs, and support translational modeling for dose and efficacy predictions. Lead cross-functional collaboration with Medicinal Chemistry, Toxicology, Pharmacology, and DMPK teams to inform go/no-go decisions and molecule design. Qualifications: PhD in Pharmaceutical Sciences, Pharmacokinetics, or related fields; 2+ years industry experience in radioligand or radioconjugate drug discovery; deep ADME expertise with knowledge of medicinal chemistry and toxicology principles is advantageous. Skills: excellent communication, ability to navigate ambiguity, strategic thinking, and leadership in cross-functional teams. High-value biopharma specifics: focus on early-stage preclinical development of radioconjugates, integration of PK/PD and safety data, regulatory compliance, and process optimization. Work setup: open to Boston MA, Louisville CO, or Indianapolis IN; no specific travel requirements noted.