Director, Translational and Clinical Genetics

Role Summary

Director, Translational and Clinical Genetics. Lead translational genetics programs within the Translational & Clinical Genetics team to identify, develop and deliver data-driven programs that impact the GSK pipeline. Provide strategic leadership across cross-functional teams, integrating genetics with genomics and clinical phenotypes to inform target and biomarker discovery, disease understanding, and treatment response optimization using precision medicine approaches. on-site presence required (minimum two days per week) at one of GSK’s US or UK sites.

Responsibilities

• Harness deep expertise in genetics with integration of genomic and clinical phenotypic data to undertake hands-on translational analyses to impact the GSK pipeline.
• Collaborate with GSK scientists and physicians to identify, develop and deliver novel data-driven programs to aid drug discovery and clinical development.
• Provide strategic leadership to cross-functional translational teams across priority therapy areas.
• Establish and oversee external scientific collaborations for data generation, access and analysis to catalyse translational insights.
• Communicate analysis findings with expert interpretation and recommendations to project teams and stakeholders.
• Deliver objectives with strong statistical, analytic, and critical thinking within the translational context.
• Stay informed about emerging technologies in translational genetics and genomics.
• Foster a culture of innovation, collaboration, and continuous professional learning within the team.

Qualifications

• Medical degree
• PhD or equivalent advanced degree in a relevant scientific discipline (e.g., translational genetics, genetic epidemiology, biomedical statistics, computational sciences, bioinformatics or machine learning)
• Publication history or clinical practice in the fields noted above
• Broad clinical knowledge across therapeutic areas and experience of clinical research to investigate translational questions
• Hands-on experience with genetic data and analyses integrating genetics with genomics and clinical phenotypes
• Ability to design and deliver innovative analyses with expert interpretation in translational medicine or drug discovery settings
• Experience with relative and absolute summary measures to aid interpretation of group differences
• Proficiency in R or Python with reproducible and scalable coding ability
• Ability to communicate complex scientific concepts to diverse audiences
• Strong collaboration and partnership skills with cross-functional stakeholders
• Understanding of drug discovery and development stages with biomarkers and precision medicine concepts

Skills

• Genetics and genomics integration with clinical data
• Data-driven translational analysis and program leadership
• Statistical analysis and critical thinking in translational contexts
• External collaboration management
• Effective scientific communication across diverse audiences

Education

• Medical degree; PhD or equivalent advanced degree in relevant field

Additional Requirements

• On-site presence at UK or US site (minimum two days per week)