Director, Technical (CMC) Project Management
Structure Therapeutics
August 13, 2026
Remote friendly (South San Francisco, CA)
United States
Operations
Position Summary
Reporting to SVP Technical Operations, the Director Technical (CMC) Project Management will lead technical CMC project management across late-stage development through commercialization and lifecycle management, including integrated project planning, execution, budgeting, risk management, cross-functional alignment, and meeting facilitation.
Job Responsibilities
- Lead end-to-end CMC project management for late-stage programs through commercial launch and lifecycle management.
- Develop and maintain integrated cross-functional project plans (drug substance, drug product, analytical, quality, regulatory, supply chain).
- Drive alignment to program strategy, timelines, and business objectives; serve as a key Tech Ops leadership team member.
- Create/manage Gantt-based project plans with timelines, milestones, dependencies, and critical paths.
- Track execution across internal teams and global CDMO partners; monitor progress vs. timelines, budgets, deliverables; identify and resolve risks/issues.
- Facilitate weekly CMC meetings and governance forums; set agendas; enforce best practices for communication/documentation.
- Partner on project and multi-year departmental budgets; track spending/accruals; align work orders to forecasts; provide regular reporting.
- Coordinate with Tech Ops functional leads and company program teams; support Procurement/Legal on work orders/contracts.
- Maintain project risk registers/mitigation strategies; drive continuous improvement and capture lessons learned.
- Establish best-in-class project management standards/tools/processes; mentor and develop PM capabilities.
Qualifications
- BS in Chemistry/Engineering or related (required). MS/PhD and PM accreditation (preferred).
- 12+ years in pharmaceutical/biotech CMC (manufacturing, process development, analytical, quality, supply chain, and/or regulatory CMC).
- 5+ years project management supporting late-stage development through commercial launch.
- Direct experience with small molecule and oral solid dosage (OSD) products.
- Experience supporting commercialization and lifecycle management.
- Strong understanding of CMC, manufacturing, regulatory, and supply requirements.
- Proficient with MS Project, Smartsheet, Excel, PowerPoint; strong project planning/timeline and budgeting/accrual tracking knowledge.
- Ability to work in fast-paced global matrix environments; strong analytical/problem-solving and communication/influence.
Travel: up to 25% globally.
Reporting to SVP Technical Operations, the Director Technical (CMC) Project Management will lead technical CMC project management across late-stage development through commercialization and lifecycle management, including integrated project planning, execution, budgeting, risk management, cross-functional alignment, and meeting facilitation.
Job Responsibilities
- Lead end-to-end CMC project management for late-stage programs through commercial launch and lifecycle management.
- Develop and maintain integrated cross-functional project plans (drug substance, drug product, analytical, quality, regulatory, supply chain).
- Drive alignment to program strategy, timelines, and business objectives; serve as a key Tech Ops leadership team member.
- Create/manage Gantt-based project plans with timelines, milestones, dependencies, and critical paths.
- Track execution across internal teams and global CDMO partners; monitor progress vs. timelines, budgets, deliverables; identify and resolve risks/issues.
- Facilitate weekly CMC meetings and governance forums; set agendas; enforce best practices for communication/documentation.
- Partner on project and multi-year departmental budgets; track spending/accruals; align work orders to forecasts; provide regular reporting.
- Coordinate with Tech Ops functional leads and company program teams; support Procurement/Legal on work orders/contracts.
- Maintain project risk registers/mitigation strategies; drive continuous improvement and capture lessons learned.
- Establish best-in-class project management standards/tools/processes; mentor and develop PM capabilities.
Qualifications
- BS in Chemistry/Engineering or related (required). MS/PhD and PM accreditation (preferred).
- 12+ years in pharmaceutical/biotech CMC (manufacturing, process development, analytical, quality, supply chain, and/or regulatory CMC).
- 5+ years project management supporting late-stage development through commercial launch.
- Direct experience with small molecule and oral solid dosage (OSD) products.
- Experience supporting commercialization and lifecycle management.
- Strong understanding of CMC, manufacturing, regulatory, and supply requirements.
- Proficient with MS Project, Smartsheet, Excel, PowerPoint; strong project planning/timeline and budgeting/accrual tracking knowledge.
- Ability to work in fast-paced global matrix environments; strong analytical/problem-solving and communication/influence.
Travel: up to 25% globally.