Director/Sr Director Pharmacometrics
Eli Lilly and Company
August 25, 2026
Full-time
On-site
Boston, MA
Clinical Research and Development
Role: Senior Scientific Leader in Pharmacometrics at Lilly, responsible for defining and leading advanced quantitative modeling strategies across drug development programs. Responsibilities: champion model-informed drug discovery (MIDD), resolve complex technical challenges related to PKPD modeling, influence regulatory interactions, and shape development decisions. Lead cross-functional collaborations, mentor scientists, and drive innovation through automation and AI/ML integration. Represent Lilly externally via publications and industry forums. Requirements: PhD in a relevant scientific discipline (e.g., pharmacometrics, bioengineering, biostatistics), minimum 5 years post-PhD experience with population PKPD modeling across various phases. Proficiency in NONMEM, Monolix, R; familiarity with mrgsolve, Julia, Phoenix NLME, MATLAB preferred. High-value specifics: focus on biologics or small molecules within early to late development stages; direct engagement with regulatory agencies; leveraging emerging technologies in modeling and automation. Collaboration/reporting: works as a strategic partner influencing senior leadership and project teams. Work setup: full-time, based at Lilly headquarters with a salary range of $177K-$308K, with potential for bonus, comprehensive benefits, and leadership in a transformative scientific environment.