Director/Sr Director Pharmacometrics
Eli Lilly and Company
August 25, 2026
Remote friendly (Indianapolis, IN)
United States
Clinical Research and Development
Role Overview
- Operate as an enterprise-level scientific leader, defining which scientific problems matter and shaping PMx strategy across programs, platforms, and the broader organization. High-visibility with influence on drug development decisions, regulatory interactions, and team capability-building.
Key Responsibilities
Scientific & Technical Leadership
- Champion MIDD approaches across programs and platforms; define and deliver novel PMx strategies shaping drug development decisions.
- Resolve complex cross-program scientific challenges (exposure-response, dose justification, regulatory submission strategies) in collaboration across functions.
- Engage proactively with regulatory agencies through meetings, responses, and advisory interactions.
Partnership & People Development
- Inspire, mentor, and elevate scientists through scientific leadership and mentorship.
- Build technical depth, scientific judgment, and confidence; share knowledge and invest in organizational capability.
Automation, Innovation & AI Integration
- Champion adoption of automation tools and AI/ML approaches delivering scalable value.
External Visibility & Scientific Leadership
- Build PMx’s external reputation via publications and leadership in industry/regulatory forums.
- Communicate complex science to diverse audiences with executive presence.
Basic Qualifications
- PhD in relevant field (PMx, biological/pharmaceutical sciences, bioengineering, biostatistics, CS/engineering, data science, or related) with 5+ years post-PhD.
- Experience in population PKPD modeling across multiple programs or development phases.
- Experience with NONMEM and/or Monolix and R.
Additional Skills & Preferences
- Experience with mrgsolve, Julia, Phoenix NLME, and/or MATLAB.
- Translate modeling outputs into clear scientific/regulatory narratives for non-specialists.
- Influence drug development and regulatory strategy with evidence beyond a single project.
- MIDD experience shaping technical strategy (e.g., regulatory submissions, health authority interactions, governance bodies).
- Strong mentorship/coaching skills; experience developing junior scientists.
- Hands-on AI/automation engagement; curiosity and judgment to translate innovation into practical value.
- Strong organizational and self-management skills; manage a complex portfolio and prioritize for impact.
Benefits (if applicable)
- Company bonus (depending on company/individual performance).
- Comprehensive benefit program including 401(k), pension, vacation, medical/dental/vision/prescription, flexible benefits, life insurance, time off/leave, and well-being benefits.
- Operate as an enterprise-level scientific leader, defining which scientific problems matter and shaping PMx strategy across programs, platforms, and the broader organization. High-visibility with influence on drug development decisions, regulatory interactions, and team capability-building.
Key Responsibilities
Scientific & Technical Leadership
- Champion MIDD approaches across programs and platforms; define and deliver novel PMx strategies shaping drug development decisions.
- Resolve complex cross-program scientific challenges (exposure-response, dose justification, regulatory submission strategies) in collaboration across functions.
- Engage proactively with regulatory agencies through meetings, responses, and advisory interactions.
Partnership & People Development
- Inspire, mentor, and elevate scientists through scientific leadership and mentorship.
- Build technical depth, scientific judgment, and confidence; share knowledge and invest in organizational capability.
Automation, Innovation & AI Integration
- Champion adoption of automation tools and AI/ML approaches delivering scalable value.
External Visibility & Scientific Leadership
- Build PMx’s external reputation via publications and leadership in industry/regulatory forums.
- Communicate complex science to diverse audiences with executive presence.
Basic Qualifications
- PhD in relevant field (PMx, biological/pharmaceutical sciences, bioengineering, biostatistics, CS/engineering, data science, or related) with 5+ years post-PhD.
- Experience in population PKPD modeling across multiple programs or development phases.
- Experience with NONMEM and/or Monolix and R.
Additional Skills & Preferences
- Experience with mrgsolve, Julia, Phoenix NLME, and/or MATLAB.
- Translate modeling outputs into clear scientific/regulatory narratives for non-specialists.
- Influence drug development and regulatory strategy with evidence beyond a single project.
- MIDD experience shaping technical strategy (e.g., regulatory submissions, health authority interactions, governance bodies).
- Strong mentorship/coaching skills; experience developing junior scientists.
- Hands-on AI/automation engagement; curiosity and judgment to translate innovation into practical value.
- Strong organizational and self-management skills; manage a complex portfolio and prioritize for impact.
Benefits (if applicable)
- Company bonus (depending on company/individual performance).
- Comprehensive benefit program including 401(k), pension, vacation, medical/dental/vision/prescription, flexible benefits, life insurance, time off/leave, and well-being benefits.