Director/Sr Director Pharmacometrics
Eli Lilly and Company
6 months ago
Remote friendly (Boston, MA)
United States
Clinical Research and Development
Role Overview:
- Director/Sr Director Pharmacometrics—define which scientific problems matter and shape PMx strategy across programs, platforms, and the broader organization. High-visibility role influencing drug development decisions, regulatory interactions, and team capability-building.
Key Responsibilities:
- Scientific & Technical Leadership:
- Champion MIDD approaches across programs and platforms; deliver novel PMx strategies that shape drug development decisions.
- Resolve complex technical/scientific challenges with cross-program impact (e.g., exposure-response, dose justification, regulatory submission strategies) in collaboration with PKPD lead and across functions.
- Engage proactively with regulatory agencies through meetings, responses, and advisory interactions.
- Partnership & People Development:
- Provide scientific leadership, mentorship, and good examples to inspire and elevate scientists.
- Mentor scientists at all levels to build technical depth, scientific judgment, and confidence.
- Enable others to succeed by sharing knowledge, opening doors, and investing in bench strength and organizational capability.
- Automation, Innovation & AI Integration:
- Champion adoption of automation tools and AI/ML approaches that deliver pragmatic, scalable value.
- Build PMx external reputation through publications and scientific leadership in industry and regulatory forums.
- Communicate complex science to diverse audiences with executive presence.
Basic Qualifications:
- PhD in a relevant scientific field (PMx, biological/pharmaceutical sciences, bioengineering, biostatistics, computer science/engineering, data science, or related) with 5+ years post-PhD experience.
- Experience in population PKPD modeling across multiple programs or development phases.
- Experience with NONMEM and/or Monolix and R.
Additional Skills & Preferences (Highly Valued):
- Experience with mrgsolve, Julia, Phoenix NLME, and/or MATLAB.
- Ability to translate quantitative modeling outputs into clear scientific and regulatory narratives.
- Proven track record influencing drug development decisions and regulatory strategy with impact beyond a single project.
- MIDD experience shaping technical strategy across programs/platforms, including regulatory submissions and health authority interactions.
- Strong mentorship/coaching skills.
- Active engagement with AI and automation in a PMx context.
- Strong organizational and self-management skills; ability to manage a complex portfolio and prioritize for maximum scientific impact.
Benefits (as listed):
- 401(k), pension, vacation; medical/dental/vision/prescription drug; flexible benefits (e.g., healthcare/dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence; well-being benefits (e.g., employee assistance program, fitness benefits, employee clubs/activities).
Application Instructions:
- If you require accommodation to submit a resume, complete the accommodation request form: https://careers.lilly.com/us/en/workplace-accommodation.
- Director/Sr Director Pharmacometrics—define which scientific problems matter and shape PMx strategy across programs, platforms, and the broader organization. High-visibility role influencing drug development decisions, regulatory interactions, and team capability-building.
Key Responsibilities:
- Scientific & Technical Leadership:
- Champion MIDD approaches across programs and platforms; deliver novel PMx strategies that shape drug development decisions.
- Resolve complex technical/scientific challenges with cross-program impact (e.g., exposure-response, dose justification, regulatory submission strategies) in collaboration with PKPD lead and across functions.
- Engage proactively with regulatory agencies through meetings, responses, and advisory interactions.
- Partnership & People Development:
- Provide scientific leadership, mentorship, and good examples to inspire and elevate scientists.
- Mentor scientists at all levels to build technical depth, scientific judgment, and confidence.
- Enable others to succeed by sharing knowledge, opening doors, and investing in bench strength and organizational capability.
- Automation, Innovation & AI Integration:
- Champion adoption of automation tools and AI/ML approaches that deliver pragmatic, scalable value.
- Build PMx external reputation through publications and scientific leadership in industry and regulatory forums.
- Communicate complex science to diverse audiences with executive presence.
Basic Qualifications:
- PhD in a relevant scientific field (PMx, biological/pharmaceutical sciences, bioengineering, biostatistics, computer science/engineering, data science, or related) with 5+ years post-PhD experience.
- Experience in population PKPD modeling across multiple programs or development phases.
- Experience with NONMEM and/or Monolix and R.
Additional Skills & Preferences (Highly Valued):
- Experience with mrgsolve, Julia, Phoenix NLME, and/or MATLAB.
- Ability to translate quantitative modeling outputs into clear scientific and regulatory narratives.
- Proven track record influencing drug development decisions and regulatory strategy with impact beyond a single project.
- MIDD experience shaping technical strategy across programs/platforms, including regulatory submissions and health authority interactions.
- Strong mentorship/coaching skills.
- Active engagement with AI and automation in a PMx context.
- Strong organizational and self-management skills; ability to manage a complex portfolio and prioritize for maximum scientific impact.
Benefits (as listed):
- 401(k), pension, vacation; medical/dental/vision/prescription drug; flexible benefits (e.g., healthcare/dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence; well-being benefits (e.g., employee assistance program, fitness benefits, employee clubs/activities).
Application Instructions:
- If you require accommodation to submit a resume, complete the accommodation request form: https://careers.lilly.com/us/en/workplace-accommodation.