Role Summary
Director/Sr. Director, Immunology Research - Cutaneous Biology: lead the cutaneous biology discovery efforts within the Immunology Research Therapeutic Area. This role operates within a cross-functional team focused on driving scientific innovation in skin and hair biology to create a robust portfolio of dermatology and aesthetics therapeutic candidates.
Responsibilities
- Provide scientific direction for cutaneous biology discovery research for skin and hair disorders
- Lead the design and execution of research projects focused on skin/hair follicle biology
- Contribute to external innovation and business development (BD) due diligence activities pertaining to skin and hair biology that drive our decision making around BD opportunities
- Help identify novel targets based on human causal biology and validate their contribution to skin quality and hair disorders using relevant in vitro, ex vivo, and in vivo models
- Guide the design, optimization, and implementation of preclinical models that capture translational biology, integrating insights from human tissue profiling data
- Design and implement flow schemes to characterize potential therapeutics for effects on cutaneous biology, leveraging both internal and external resources
- Partner with the Immunology in vivo pharmacology team to execute critical experiments
- Work with a cross-functional team to generate comprehensive data packages that advance novel therapeutic approaches and support Go/No Go decision-making
- Foster a collaborative, creative, and scientifically rigorous team culture committed to excellence and innovation
- Develop team capabilities and ensure appropriate resource allocation
Qualifications
- Required: Degree in PhD, PharmD in immunology, molecular biology, or related scientific discipline
- Required: 10+ years of relevant experience in biotech or pharma
- Preferred: Experience leading discovery research programs from early-stage research through candidate selection
- Preferred: Knowledge of current therapeutic landscape in dermatology and medical aesthetics
- Preferred: Experience with novel therapeutic modalities (cell therapy, genetic medicine, precision medicine, local delivery technologies, etc.)
- Preferred: Experience with IND submission and preclinical data package generation
- Preferred: Deep expertise in cutaneous biology with demonstrated experience in developing complex ex vivo human skin/hair follicle assays and in vivo models of skin/hair disorders
- Preferred: Familiarity with data-driven discovery approaches, including integration of genetic or multi-omics insights
- Preferred: Experience building and managing research projects with proven success in project execution in a multi-disciplinary team environment
- Preferred: High degree of organizational skills, attention to detail, and critical thinking, with ability to prioritize work and meet target timelines
- Preferred: Excellent interpersonal and communication skills, with the ability to drive cross-site collaboration in a matrixed research environment