Director/Senior Director, In Vitro Biology & Molecular Pharmacology

Role: Senior leadership role overseeing In Vitro Biology and Molecular Pharmacology within Schrödinger's Therapeutics Group, focusing on small molecule drug discovery for challenging targets and novel modalities. Responsibilities include setting strategic direction, target assessment, designing and executing hit finding campaigns across DEL, fragment screening, HTS/MTS, and chemoproteomics platforms, and providing scientific oversight for complex target classes such as protein-protein interactions and degraders. The role involves managing a team, CRO partnerships, defining assay cascades, and driving technological advancements. Requirements: PhD in relevant disciplines, 10+ years in drug discovery industry, extensive experience with assay development, hit finding modalities, and leading in vitro biology teams. Preferred skills include knowledge of protein degraders (PROTACs), data platforms like LiveDesign, and experience with in vivo PK/PD studies. The position emphasizes strategic and scientific leadership, cross-disciplinary collaboration, and talent development. High-value specifics involve early to mid-stage small molecule programs, undrugged or difficult targets, and integrating platforms like chemoproteomics and computational methods. The role reports to senior leadership and involves collaboration across multiple functional areas. Work setup details are not specified.