Director/Senior Director, Business Systems

Role Summary

The Director/Senior Director, Business Systems will lead the strategy, implementation, and optimization of enterprise business systems supporting Immunome’s growth. This role oversees the NetSuite platform and other Finance and G&A-related systems and data, ensuring they scale with the organization’s evolving needs. The position manages a small, high-performing team and partners across the company to deliver efficient, compliant, and insight-driven systems and processes to support commercialization and pipeline growth.

Responsibilities

• Own the overall vision, strategy, and roadmap for financial systems, including ERP and certain G&A applications (e.g., procurement, expense management, contract management systems, HRIS systems and integrations, budgeting and forecasting tools).
• Lead system selection, implementation, and continuous improvement initiatives, ensuring alignment with business processes and compliance requirements (SOX, audit, Sunshine Act, etc.).
• Oversee sales reporting and analytics systems, ensuring integration of data across sales, gross-to-net components, and financial systems.
• Manage a small team responsible for the administration, configuration, and support of business systems.
• Partner with the Commercial, Compliance, and Technical Operations teams to prepare the systems and data landscape to support the commercial launch of varegacestat.
• Partner with leaders across the company to select systems, determine strategy for integrations and data, streamline workflows, automate processes, and enhance data integrity across platforms.
• Establish and enforce best practices for system governance, change management, and master data management.
• Oversee vendor relationships and ensure service delivery meets organizational needs and SLAs.
• Provide guidance on system integration strategy across enterprise applications (ERP, CRM, HRIS, etc.).
• Develop and maintain dashboards and reporting capabilities to support decision-making and financial planning.
• Stay current on emerging technologies and industry trends to drive innovation in financial operations.

Qualifications

• Bachelor’s degree in Finance, Accounting, Information Systems, or related field; MBA or CPA preferred.
• 10+ years of experience in financial systems management, including ERP implementation and support (NetSuite, SAP, Oracle, or Workday preferred).

Knowledge And Skills

• Demonstrated success in leading system transformations within a high-growth or complex organization—biotech or life sciences experience strongly preferred.
• Strong understanding of financial and commercial processes (GL, AP, AR, FP&A, procurement, compliance, and revenue management/gross-to-net reporting).
• Experience designing and governing integrated system architectures and data models across Finance, Commercial, and G&A platforms.
• Proven leadership skills with experience managing small teams, multiple stakeholders, and leading cross-functional initiatives from design through execution
• Excellent communication and stakeholder management skills, with the ability to translate business needs into technical solutions.
• Strategic thinker with a hands-on approach and a focus on continuous improvement.
• Demonstrated experience managing vendor relationships and system roadmaps. Ability to maintain a high level of confidentiality