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Director, Real World Data Platform and Portfolio Lead

GSK plc
October 15, 2026
Full-time
On-site
USA - Pennsylvania - Upper Providence; UK - Hertfordshire - Stevenage; UK – London – New Oxford Street
Clinical Research and Development
For candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage, UK. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029.
Business Introduction
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together.
Summary
You will be accountable for the strategic execution and coordination of our internal and external RWD platform partnerships to impact R&D and CPO activities, delivering insights, models and evidence and ensuring maximum scientific value demonstration from use of RWD as a key input into decision making, pipeline progress and portfolio growth.
As the external data landscapes evolves globally, increasing competitive advantage is obtained by thoughtful data partnerships that align with GSK’s translational, development and commercialisation goals. GSK facilitates a global RWD platform of partners, systems and collaborators which collectively enables a wide availability of data which acts as critical enabler for insight, models and evidence generation.
Reporting to the Executive Director and Head, RWD Strategy and Partnerships, this is a critical role of coordinating our RWD strategy and execution across our wide network of internal and external stakeholders. This role will be tasked with ownership and operational execution of RWD investment and key capability partnership aligned with GSK’s wider vision The role will be directly accountable for our core data partnerships which sit above one particular therapy area representing health systems more widely and across key regions where RWD is being made available. Where relevant this role will support integration and elevation of these datasets internally as well as providing operational leadership to our above TA portfolio.
The successful candidate must demonstrate exceptional data strategy and operations skills and work with key functions in Translational and Development Sciences and Medical Affairs to ensure excellence in data acquisition and access whilst maximising the overall availability of external data.
Core Accountabilities
Lead and execute above disease area/tumour type RWD partnerships, build partnerships built around expanding RWD capabilities and identifying new opportunities to access population level health datasets. Where relevant partner with Translational Sciences on RWD partnerships linked to -omics, biobanks and other translational cohorts.
Ensure partnerships offer scale to drive GSK’s RWE ambition and ensure operational execution of evidence generation relating to data access and analysis
Partner in key regions and with regional leaders where population level health data can be leveraged for research, positioning GSK as a leading partner in large observational research and quantitative innovation and enabling
Act as strategic lead for the internal RWD domain for GSK’s data offices, ensuring engineering, programming and AI teams have clear input on wider data strategy plans.
Partner with Real World Data Engineering team to guide pipeline strategy and data product roadmap
Represent RWD and Development Sciences in the cross-functional data governance forum, ensuring centralised expectations of good data governance are translated into RWD specific domain plans.
Inform data linkage strategy across our RWD portfolio and in prospective observational studies
Partner with DevOps to ensure use of RWD portfolio for clinical operations planning and execution
Deliver and maintain the baseline inventory of RWD assets that underpins portfolio assessment and decision making
Facilitate partnerships which enhance usability and impact of RWD for R&D, Medical and Commercial teams, act as strategic link between functions and share and combine needs when appropriate
Work with therapy area aligned data strategy leads and other internal data owners around common deliverables to inform upcoming governance decisions and support business case and financial modelling for new investments ahead of upcoming governance.
Inform technology and infrastructure strategy to prioritise re-usable infrastructure and enable efficient use of third-party vendors and partner hosted trusted research environments
Ensure platform and tools strategy compliantly uses RWD and keep internal networks abreast of access opportunities, including but not limited to agentic interfaces.
Prioritise and monitor resource management across active RWD initiatives based on enterprise value and wider data and analytics strategy
Set and monitor clear KPI’s around partnerships and data value, bring key delivery metrics to organisational execution
Influence data governance and AI readiness efforts to ensure high quality, analysis ready and FAIR data.
Basic Requirements:
Advanced degree (MSc or PhD) in life sciences or quantitative field (Epidemiology, Biostatistics, HEOR, data science preferred)
Demonstrated track record of data strategy ownership and execution in application to drug development including experiences in wide and complex cross-functional organisations
Leadership skills in influencing and mobilising stakeholders to a common goal
Experience and knowledge of RWD sources and partners, spanning multiple geographies, understanding of country and regional health data landscapes, critically assess opportunities for research
Exceptional portfolio project management and organisational skills, particularly within a complex dynamic organisation.
Ability to communicate with clarity, vision and purpose
Understanding of current regulatory and payer guidance of use or Real World Evidence/Data in decision making.
Knowledge of key data strategy concepts in relation to RWD; FHIR, tokenisation and linkage, synthetic control arms, Common Data Models (CDMs) and context specific LLMs
Preferred Requirements:
Strong knowledge and experience of observational research methodology, including study designs and impact of data quality on research validity.
‘Hands on’ programming, coding skills and demonstrated experience with RWD
Experience with data engineering and architecture, including working in or deploying trusted research environments
Experience in AI/ML enablement and deployment of AI workflows
Demonstrated experience of strategic partnerships with human patient level data including biomarkers, -omics and other biological measures and samples linked to clinical or real-world outcome data
Closing date for applications is Thursday 29th October
Skills
Artificial Intelligence (AI), Business Analysis, Data Analysis, Data Mining, Digital Fluency, Digital Transformation, Organization Transformation, Process Improvements, Process Innovation, Product Development, Product Management, Project Management, Regulatory Compliance Management, Security System Design, Strategic Planning
Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.
People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.
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