Director, Quantitative Clinical Pharmacology: PK/PD Modeling & Strategy

Role: Director of Quantitative & Clinical Pharmacology, leading clinical pharmacology and pharmacometrics from early to late-stage development (Ph3 and registration) for Sarepta's gene and molecular therapies. Responsibilities: develop and execute quantitative pharmacology strategies, lead clinical and translational PK/PD modeling, perform model-based analyses including population PK, PK/PD, meta-analyses, and disease modeling; support regulatory strategies and global health authority engagements; contribute to protocol development, study execution, and data review; maintain scientific leadership through publications and conferences. Requirements: PhD in Pharmaceutical Sciences, Mathematics, Engineering, or related field; 7+ years in clinical pharmacology or pharmacometrics; strong PK/PD modeling expertise, regulatory experience, proficiency with NONMEM & R; excellent communication and collaboration skills. Preferred: siRNA or CNS experience. HighValue: clinical pharmacology leadership, modeling and simulation, regulatory interactions, therapeutic focus on gene/muscle/CNS therapies, global regulatory strategy. WorkSetup: hybrid, onsite at US facilities with occasional in-person company events.