Director, Quantitative Clinical Pharmacology: PK/PD Modeling & Strategy

Role: Lead clinical pharmacology and pharmacometrics for Sarepta's drug development programs, focusing on dose selection, PK/PD modeling, and translational strategies through late-stage clinical trials (Ph3) and registration. Responsibilities: develop and execute quantitative pharmacology strategies, perform model-based data analyses (population PK, PK/PD, meta-analysis, disease modeling), and support regulatory interactions; oversee clinical and translational development, protocol design, data review, and reporting; serve as a scientific leader and represent the function in external forums. Qualifications: PhD in Pharmaceutical Sciences, Mathematics, Engineering, or related field; 7+ years in clinical pharmacology or pharmacometrics; expertise in PK/PD modeling, model development, and regulatory engagement; proficiency in NONMEM and R preferred; siRNA or CNS experience advantageous. HighValue: clinical pharmacology leadership, dose optimization, pharmacometric modeling, late-stage development, regulatory strategy, global stakeholder management. WorkSetup: hybrid (U.S. based), onsite at Sarepta facilities with occasional in-person events; no specific travel percentage stated.