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Director - PKDM - Small Molecule Portfolio Strategy & Leadership

Amgen
August 31, 2026
Full-time
Remote friendly (South San Francisco, CA)
Worldwide
Clinical Research and Development
Role: Director of PKDM for Small Molecule Portfolio Strategy & Leadership, focusing on advancing small molecule drug candidates from discovery through clinical development and regulatory submission. Responsibilities include providing scientific and strategic leadership to cross-functional teams, supporting candidate selection and optimization, driving regulatory submissions (INDs, NDAs), and integrating emerging technologies to enhance development outcomes. The role also involves external collaboration with business development and contributing to organizational strategy. Qualifications: PhD, PharmD, or MD with 5+ years in pharmaceutical sciences, pharmacokinetics, or related fields; or master's with 8+ years; or bachelor's with 10+ years industry experience. Preferred skills include proven leadership across discovery and development, extensive regulatory experience, deep expertise in drug disposition and PK, and strong external scientific presence. Experience working across multiple therapeutic areas or modalities is desirable. The role emphasizes scientific innovation, project leadership, and strategic decision-making in the small molecule space, with an expectation of fostering high-performing teams and influencing key portfolio decisions. Location: Not specified.