Director, Medicinal Chemistry
Vertex Pharmaceuticals
August 28, 2026
Full-time
Remote friendly (San Diego, CA)
Worldwide
Other
Role: Director of Medicinal Chemistry responsible for leading small-molecule discovery programs, guiding compound design, optimization, and candidate selection. Responsibilities include defining chemistry strategies, collaborating cross-functionally with biology, DMPK, toxicology, and pharmaceutical sciences, managing external partnerships, and supporting IP strategy. Requirements: Ph.D. in Chemistry or related field with 9+ years (PhD), 12+ (Master's), or 15+ (Bachelor's) years of industry experience; proven success in small-molecule drug discovery and program advancement; leadership in matrixed teams; strong communication and strategic decision-making skills. High-Value: small-molecule discovery, candidate selection, cross-disciplinary collaboration, on-site work, no travel specified.