Director, Master Data Management

Job Description Director, Master Data Management General / Position Summary Vertex is entering a transformative phase in its data journey—where trusted, governed master data is foundational to enabling enterprise-wide analytics, AI, and operational excellence. We are seeking a visionary and execution-focused Director of Master Data Management (MDM) to lead our enterprise MDM strategy and operations across Customer, Supplier, and Product domains. This role will lead the modernization of our Global Customer Master, oversee the expansion of our Supplier MDM, and drive the design and implementation of a new Product MDM capability. The Director will also be responsible for integrating AI/ML and large language model (LLM) technologies into MDM operations to improve data quality, stewardship automation, and semantic enrichment. Key Duties & Responsibilities Strategic Leadership Define and execute the enterprise MDM strategy aligned with Vertex’s data and business priorities. Lead the modernization and cloud migration of the Customer Master. Oversee the expansion of Supplier MDM to support Source-to-pay, Manufacturing, Supply Chain, and Quality functions. Lead the design and phased implementation of a new Product MDM capability. Champion the use of AI/ML and LLM technologies to automate data matching, enrichment, anomaly detection, and stewardship workflows. Team & Program Management Build and lead a high-performing MDM team, including domain leads, platform managers, MDM analysts, and stewardship coordinators. Establish and manage a cross-functional MDM governance model in collaboration with business data owners and stewards. Partner with the Data Governance, Ontology, Data Engineering, and Compliance teams to ensure alignment with enterprise data standards and regulatory requirements. Platform & Technology Oversight Own the MDM platform roadmap and architecture. Ensure scalability, performance, and resilience of MDM platforms and integrations with enterprise systems (e.g., Veeva, Salesforce,Oracle ERP, Snowflake, Databricks). Evaluate and implement AI/LLM-based tools for intelligent data mastering, semantic matching, and metadata generation. Operational Excellence & Innovation Define and track KPIs for master data quality, stewardship efficiency, and platform performance. Drive continuous improvement in MDM processes using agile methodologies and data-driven insights. Stay ahead of industry trends in AI, data governance, and MDM to evolve Vertex’s capabilities and influence enterprise data strategy. Knowledge & Skills Deep expertise in Master Data Management (MDM) principles, data lifecycle management, and multi-domain MDM (Customer, Supplier, Product) in the biopharmaceutical or life sciences industry. Proven experience with MDM platforms, including data modeling, match/merge configuration, survivorship rules, and integration with enterprise systems (e.g., Veeva, Oracle ERP, Salesforce, Snowflake). Strong understanding of data governance frameworks, data quality management, metadata management, and stewardship operating models. Demonstrated ability to lead large-scale MDM transformation initiatives, including cloud migrations and enterprise-wide adoption. Familiarity with AI/ML and large language model (LLM) technologies and their application in MDM use cases such as intelligent data matching, semantic enrichment, anomaly detection, and stewardship automation. Knowledge of cloud data platforms and services (e.g., AWS, Snowflake, Databricks) and modern data architecture patterns. Strong awareness of data privacy, security, and compliance requirements (e.g., GDPR, HIPAA, Sunshine Act) and experience embedding these into MDM practices. Excellent leadership and team-building skills, with experience managing cross-functional teams and vendor/partner relationships. Strong communication, stakeholder engagement, and change management skills, with the ability to translate complex data concepts into business value. Proficiency in Agile methodologies, project management, and continuous improvement practices. Education & Experience Bachelor’s degree in computer science, Information Systems, or related field required. Master’s degree or equivalent experience in Data Science, Information Management, or Business preferred. 10+ years of experience in data management, with 6+ years in MDM leadership roles. Experience in life sciences or other highly regulated industries strongly preferred. #LI-HYBRID Pay Range: $184,000 - $276,000 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com Help Us Achieve Our Mission Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has approved medicines that treat the underlying causes of multiple chronic, life-shortening genetic diseases — cystic fibrosis, sickle cell disease and transfusion-dependent beta thalassemia — and continues to advance clinical and research programs in these diseases. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including APOL1-mediated kidney disease, acute and neuropathic pain, type 1 diabetes, myotonic dystrophy type 1 and alpha-1 antitrypsin deficiency . Founded in 1989 in Cambridge, Mass., Vertex's global headquarters is now located in Boston's Innovation District and its international headquarters is in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 14 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on Facebook, Twitter/X , LinkedIn, YouTube and Instagram. The diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people’s lives. Our vision is clear: to be the place where an authentic, diverse mix of talent want to come, to stay, and do their best work.