Director, LNP Discovery

Position Summary
- Lead mRNA delivery efforts, overseeing development of novel LNP (lipid nanoparticle) systems for extrahepatic delivery.

Responsibilities
- Oversee development of novel LNPs (lipid chemistry, composition, formulation process)
- Oversee development of cell-based assays and animal models for LNP testing
- Lead LNP delivery biology (protein design and bioconjugation) to optimize LNP performance
- Collaborate cross-functionally with pharmacology and programming to achieve key milestones
- Drive RNA extrahepatic delivery strategy with emphasis on IP and key deliverables
- Stay current on RNA delivery literature; prepare technical reports/white papers
- Prepare technical documents and manuscripts for IP filings and publications
- Present scientific findings internally and externally at conferences/events

Minimum Qualifications
- PhD in Pharmaceutical Sciences, Biochemistry, Engineering, Chemistry, or related field
- 10+ years’ experience with lipid nanoparticles, siRNA, and protein design
- Demonstrated translation of animal models from mouse to non-human primate
- Excellent oral and written communication skills
- Innovation track record in LNP research (bioconjugation, protein/binder design)
- Strong record keeping (eLN)
- Proven team leadership in research
- Ability to synthesize inputs and recommend LNP research strategies
- Ability to operate at detail and high-level settings; navigate effectively
- Strategic thinking, influence, proactive ownership mindset

Preferred Qualifications
- Biotech industry experience
- Knowledge of the drug development process

Benefits/Compensation
- Base pay range: $195,000 to $215,000+ bonus, equity and benefits