Director, Launch Excellence

Role Summary

A Director, Launch Excellence is sought to plan and execute the successful commercial launch of Amylyx’s first product in the endocrinology space. This role will be hired in 2026 and will partner cross-functionally to ensure launch readiness ahead of a potential 2027 product launch. The position serves as the central coordinator for launch activities—driving disciplined execution, clear ownership, and visibility across Commercial, Medical, Clinical, Regulatory, Manufacturing, Market Access, Finance, Legal, and IT. It is a hands-on role requiring strong project leadership and the ability to operate effectively in a fast-growing biotech environment. Location: Remote within the United States, with regular attendance at the Cambridge, MA office; preference for candidates in the New England region who can be in person as needed.

Responsibilities

• Launch Planning & Execution
• Lead the end-to-end launch execution plan, including timelines, milestones, dependencies, and risk mitigation activities.
• Translate high-level launch strategy into actionable, trackable workstreams with clear ownership.
• Maintain and continuously refine integrated launch plans from pre-approval through post-launch phases.
• Cross-Functional Program Leadership
• Act as the single point of coordination across all launch-related functions.
• Facilitate regular launch governance forums (e.g., launch team meetings, executive readouts).
• Ensure continuous alignment across Commercial, Medical Affairs, Market Access, Supply Chain, Regulatory, and other key stakeholders.
• Readiness & Risk Management
• Proactively identify launch risks, gaps, and interdependencies; develop mitigation plans and escalate as needed.
• Track launch readiness metrics and ensure timely decision-making.
• Support scenario planning tied to regulatory timing, supply readiness, and market dynamics
• Tools, Process & Communication
• Implement and manage launch project management tools, dashboards, and reporting mechanisms.
• Drive consistent ways of working, documentation standards, and decision logs.
• Prepare detailed and clear executive-level communications and launch status updates
• Continuous Improvement
• Capture lessons learned and best practices to support future indications or lifecycle expansion.
• Help build scalable launch excellence capabilities appropriate for a growing biotech organization.

Qualifications

• Required: Bachelor’s degree; Advanced degree (MBA, MPH, MS) preferred.
• Required: 10+ years of experience in pharmaceutical or biotech launch, commercial operations, or enterprise project management.
• Required: Direct experience supporting product launch readiness in the U.S. market.
• Required: Proven ability to lead complex, cross-functional initiatives without direct authority.
• Required: Strong organizational, communication, and stakeholder management skills.
• Required: Fluency with project management tracking tools (e.g., MS Project, Smartsheets, MS Excel), and advanced MS PowerPoint skills.
• Required: Comfortable operating in ambiguity and adapting as strategy and timelines evolve.

Work Location and Conditions

• Remote work opportunities within the United States; must be able to attend meetings at Cambridge, MA on a regular basis. Preference for candidates in the New England region who can be in person as needed.
• When working remotely, access to a work setting that enables privacy, reliable internet, phone, and video conferencing is required.