Director, Immunoassay-based Biomarker Discovery and Analysis - Neuroscience
Eli Lilly and Company
August 21, 2026
On-site
Boston, MA
Clinical Research and Development
Responsibilities:
- Design, develop, and validate novel immunoassay-based biomarker methods; apply them to early- and late-phase clinical trials in neurodegenerative diseases (Alzheimer’s, Parkinson’s, ALS, and rare brain disorders).
- Work with project team leads and associates to perform experiments supporting preclinical and clinical characterization and evaluation of therapeutic molecules through biomarker assay development.
- Assist with planning and execution of immunoassay method development, optimization, validation, and cohort sample analyses with internal and external partners.
- Conduct on-site laboratory work; summarize and report method status/results to internal partners.
- Implement assay validation procedures to deliver high-performance biomarker assays for preclinical and clinical sample analyses.
- Collaborate cross-functionally with medical, operations, statistics, and regulatory teams and external partners (CROs, academic institutions) to ensure biomarker validation and integration into clinical programs.
Basic Qualifications:
- Master’s and/or PhD in Neuroscience, Biochemistry, or related field.
- 0–5+ years of industry, academic, or postdoctoral experience in biomarker development; recognized expertise in immuno-assay-based methods for brain diseases.
Additional Skills/Preferences:
- Understanding of antibodies/affinity molecules for immunoassay design and protein biomarker quantification; hands-on immunoassay development and validation experience for clinical diagnostics, clinical trials, or preclinical sample analysis.
- Technical skills in qualitative (e.g., electrophoresis techniques, Western blot) and quantitative (e.g., ELISA, MSD, Ella, Simoa) immunoassay analyses.
- Proven leadership mentoring biomarker research teams.
- Experience with ultrasensitive technologies (e.g., NuLISA) and protein separation/purification (e.g., HPLC, immunoprecipitation) is a plus.
- Excellent communication and collaboration skills; able to present to influence internal and external stakeholders.
Application Instructions:
- If you require accommodation to submit a resume, complete the workplace accommodation request form: https://careers.lilly.com/us/en/workplace-accommodation
- Design, develop, and validate novel immunoassay-based biomarker methods; apply them to early- and late-phase clinical trials in neurodegenerative diseases (Alzheimer’s, Parkinson’s, ALS, and rare brain disorders).
- Work with project team leads and associates to perform experiments supporting preclinical and clinical characterization and evaluation of therapeutic molecules through biomarker assay development.
- Assist with planning and execution of immunoassay method development, optimization, validation, and cohort sample analyses with internal and external partners.
- Conduct on-site laboratory work; summarize and report method status/results to internal partners.
- Implement assay validation procedures to deliver high-performance biomarker assays for preclinical and clinical sample analyses.
- Collaborate cross-functionally with medical, operations, statistics, and regulatory teams and external partners (CROs, academic institutions) to ensure biomarker validation and integration into clinical programs.
Basic Qualifications:
- Master’s and/or PhD in Neuroscience, Biochemistry, or related field.
- 0–5+ years of industry, academic, or postdoctoral experience in biomarker development; recognized expertise in immuno-assay-based methods for brain diseases.
Additional Skills/Preferences:
- Understanding of antibodies/affinity molecules for immunoassay design and protein biomarker quantification; hands-on immunoassay development and validation experience for clinical diagnostics, clinical trials, or preclinical sample analysis.
- Technical skills in qualitative (e.g., electrophoresis techniques, Western blot) and quantitative (e.g., ELISA, MSD, Ella, Simoa) immunoassay analyses.
- Proven leadership mentoring biomarker research teams.
- Experience with ultrasensitive technologies (e.g., NuLISA) and protein separation/purification (e.g., HPLC, immunoprecipitation) is a plus.
- Excellent communication and collaboration skills; able to present to influence internal and external stakeholders.
Application Instructions:
- If you require accommodation to submit a resume, complete the workplace accommodation request form: https://careers.lilly.com/us/en/workplace-accommodation