Director I, Lipid Nanoparticles

Role Summary

Director I, Lipid Nanoparticles. Lead non-viral delivery efforts for mRNA/LNP development; manage a team of ~10 scientists and drive a pipeline of development candidates in collaboration with multiple functions.

Responsibilities

• Lead an internal team of experienced scientists and oversee the design, optimization and production of mRNA and targeted LNP to support in vitro and in vivo studies.
• Define and implement strategies to develop novel LNP formulations and advance targeted LNP delivery by leveraging internal expertise in lipid chemistry, antibody engineering and bioconjugation for in situ mRNA delivery.
• Establish and drive productive collaborations with internal multi-disciplinary project teams and external partners to achieve key milestones.
• Stay up to date on latest development in LNP and other non-viral delivery technologies.
• Dive deeply into science and present scientific findings internally and externally.
• Mentor and coach staff to ensure the team achieve strategic priorities.

Qualifications

• PhD in biochemistry, chemical engineering, material science or related field.
• Greater than 10 years postdoc/industry experience focusing on lipid nanoparticle systems for mRNA delivery.
• Strong experience in lipid chemistry, formulation development and analytical techniques.
• Deep understanding of conjugation chemistry.
• Experience in mRNA/LNP scale up production and process development.
• Demonstrated ability to lead a high performing team working in a fast-paced environment.
• Proven ability to work collaboratively across teams to meet project deliverables and timelines.
• Strong communication and decision making skills.
• Previous experience in targeted LNP for extra hepatic delivery is highly preferred.

Prior experience in leading or co-leading a portfolio project to the stage of candidate selection is highly preferred.

Skills

• Lipid chemistry
• Formulation development
• Analytical techniques
• Conjugation chemistry
• Project leadership and collaboration
• Scientific communication

Education

• PhD in biochemistry, chemical engineering, material science or related field.