Director, HTA, Value & Evidence (HV&E), Solid Tumors

Role Summary

The Director, HV&E, Solid Tumors will support the Oncology Division's strategic goals by driving optimal patient access to Pfizer medicines. They will provide strategic guidance and robust evidence development to enable global access, focusing on demonstrating the value of an innovative therapy being studied for multiple solid tumors. The role involves developing and executing the global evidence generation strategy, overseeing evidence generation activities and dissemination of technical deliverables. As part of Pfizer's Global Access & Value team, the Director will manage health economics and outcomes research (HEOR) to generate data supporting patient access, collaborating with GAV, cross-functional, and country teams to promote innovation and improved patient healthcare.

Responsibilities

• Provide strategic input into clinical trial designs (e.g., patient populations, comparators, endpoints) and analysis plans to enable successful negotiations, reimbursement, and appropriate patient access with global payer and regulatory decision makers.
• Develop and execute the clinical outcomes assessment strategy and incorporate humanistic and economic endpoints into clinical trials across all phases of product development to build comprehensive trial-based evidence aligned with overall asset strategy and to ensure global reimbursement and access requirements.
• Lead the development and execution of the Value & Evidence Strategy (VES) to support the value of this innovative therapy in close partnership with the cross-functional matrix team and local country/regional teams.
• Lead the design and execution of global HEOR studies (e.g., network meta-analyses, non-interventional studies, economic models) from concept through publication.
• Lead the timely development of reimbursement deliverables to successfully support reimbursement and access requirements in conjunction with the regions/countries.
• Partner with internal stakeholders to ensure appropriate customer facing dissemination of HEOR materials per regulatory guidance and internal SOPs.
• Develop strategic partnerships and research collaborations with key external experts, healthcare policy makers, payers, and various academic and community oncology settings to support asset strategies.

Qualifications

• Required: Graduate degree required (e.g., MSc, MPH, PhD)
• Required: 7+ years of experience with MSc/MPH/MBA degree; 5+ years with PharmD/PhD in HEOR or relevant related fields (health economics, epidemiology, health services research, or other research-focused public health field)
• Required: Demonstrated in depth understanding of fundamental health services research methods and tools, including health economic modeling, patient-reported outcomes, statistics, and real-world evidence studies including technical and methodological aspects of registries and observational study design, implementation, analysis and interpretation. Capable of independently managing complex non-interventional study projects
• Required: Knowledge and understanding of drug development process
• Required: Excellent interpersonal skills required: ability to understand and respond to multiple internal and external customers
• Required: Excellent oral and written English communication skills
• Required: Demonstrated ability to assess anticipated value for projects/programs to ensure alignment to business priorities and prioritize accordingly
• Required: An “execution mindset” focused on getting things done quickly and simply
• Required: Strong project management abilities (contracting, budgeting, vendor management) essential. Demonstrated ability to manage multiple projects (multitask) involving complex processes, significant budget, competing deadlines and rapidly shifting priorities
• Required: Ability to influence key members of medical, clinical, and commercial teams constructively and without conflict
• Required: Skilled in functioning within a matrix organization and managing through influence
• Required: Organized and detail oriented with the ability to anticipate needs and to work proactively to prioritize and address/resolve issues
• Required: Change oriented and comfortable responding to unexpected demands with tight timelines; team player
• Preferred: Knowledge and experience in the oncology therapeutic area is highly preferred along with experience with solid tumor products
• Preferred: Experience with various real-world data types and sources and a publication track record of working with these sources is highly preferred
• Preferred: Experience interacting with country teams and knowledge of global HTA requirements and HTA organizations (eg, NICE, GBA, HAS, CDA, PBAC, ICER)

Skills

• Strategic thinking and stakeholder influence within a matrix organization
• HEOR methods and health economic modeling; experience with real-world evidence and observational studies
• Knowledge of drug development process; ability to engage with cross-functional teams
• Excellent interpersonal and English communication skills (oral and written)
• Strong project management and vendor management; ability to manage multiple projects with varying deadlines

Additional Requirements

• Ability to travel based on business needs
• Hybrid work arrangement requiring onsite presence 2 to 3 days per week