Director, Health Eco and Outcomes Research

Role Summary

Director of Health Economics and Outcomes Research (HEOR) at Alkermes, leading evidence generation for the alixorexton program (formerly ALKS 2680). You will report to the Head of HEOR and develop materials to support engagements with physicians, regulatory agencies, reimbursement bodies, and patients/advocates. The role requires a strong HEOR technical background, data science and visualization skills, and the ability to foster and manage internal and external relationships. This hybrid role is based in Waltham, MA, with onsite work at least 3 days per week.

Responsibilities

• Executing on the HEOR plan for the alixorexton program, with patient populations including narcolepsy type 1 (NT1), narcolepsy type 2 (NT2), and idiopathic hypersomnia (IH).
• Identifying and addressing evidence gaps and prioritizing real-world studies to inform treatment patterns, disease burden, patient-reported outcomes, and unmet needs.
• Developing and delivering high-quality HEOR evidence and value communication strategies to support optimal access and reimbursement aligned with the alixorexton program objectives.
• Gathering and synthesizing insights from payers, healthcare professional thought leaders, and HEOR experts.
• Collaborating with internal teams on publication strategies to ensure that dissemination of HEOR evidence is timely and has maximum impact across our key stakeholders with presentations at conferences and peer-reviewed manuscripts.
• Selecting and managing external research partners to ensure high-quality and timely study delivery.

Qualifications

• Required: MA/MS degree in HEOR/related field and 8+ years of pharmaceutical industry experience in a HEOR role with direct research experience.
• Preferred: PhD/PharmD in HEOR/related field and 5+ years of similar experience.
• Preferred: Strong record of high-impact publications in peer-reviewed journals.
• Preferred: Excellent communication, presentation, and collaboration skills across internal and external stakeholders.
• Preferred: Prior experience supporting a competitive product launch.
• Preferred: Prior experience in rare disease or neurological disorders, including sleep-wake disorders such as narcolepsy and idiopathic hypersomnia, is a plus but not required.
• Preferred: Excellent project management skills.

Skills

• Developing budget impact models (BIMs) and cost-effectiveness analyses (CEAs).
• Conducting indirect treatment comparisons (ITCs).
• Developing Academy of Managed Care Pharmacy (AMCP) Dossiers and pre-approval information exchange (PIE) slide decks.
• Real-world evidence (RWE) generation using diverse data sources including claims data, electronic health records (EHR), registries, chart reviews, and qualitative research.