Director. Global Clinical Safety Scientist

Role: Lead safety scientist within Clinical Safety & Pharmacovigilance for Madrigal's biopharma programs, focusing on safety assessments for metabolic disease therapeutics, notably Rezdiffra for MASH. Responsibilities: authoring and reviewing safety documents (protocols, ICFs, CSRs), evaluating clinical safety data, supporting regulatory submissions (IND, NDA, MAA), and collaborating on safety signal detection and response. Key tasks include safety data analysis, safety content development, and cross-functional stakeholder engagement. Requirements: minimum 12 years in clinical safety/pharmacovigilance, strong knowledge of global safety regulations, experience with safety databases (Argus preferred), and excellent communication skills. Preferred: advanced degrees (PharmD, PhD), experience with safety processes and external team management. High-Value: expertise in metabolic disease, clinical trial phases, and safety reporting; involvement in regulatory filings; cross-functional collaboration; and ability to interpret health records and MedDRA terminology. Work setup: full-time, with up to 10% travel.