Director, Global Clinical Physician - Early Clinical Development Oncology
Bristol Myers Squibb
August 06, 2026
Remote friendly (Brisbane, CA)
United States
Clinical Research and Development
Position Summary
- Serves as a primary source of medical accountability and oversight for multiple clinical trials.
- Manages Phase I/II studies with demonstrated decision-making capabilities.
- Provides medical and scientific expertise to cross-functional BMS colleagues.
- Maintains matrix management responsibilities across internal and external networks.
Duties/Responsibilities
Medical Monitoring
- Acts as an independent Medical Monitor for clinical trials (Phase 1 through Proof-of-Concept), articulating clinical development strategy; analyzing/interpreting/acting on clinical trial data; serving as principal functional author for regulatory submissions, study reports, and publications.
- Provides oversight and medical accountability for multiple early development trials.
- Manages site interactions with Clinical Scientist(s) for medical questions and education, including safety management.
- Assesses key safety-related serious adverse events and oversees safety narratives.
- Collaborates with Study Delivery Team (SDT) and may support Development Team.
- Provides medical strategic oversight in protocol development (e.g., inclusion/exclusion; safety-related considerations) and supports study execution (site activation, enrollment status, adjudication of protocol violations/deviations).
- Fulfills GCP/compliance obligations and maintains required training.
- Defines and establishes relationships with key global Phase 1 Centers.
Clinical Development Expertise & Strategy
- Designs and develops clinical studies/research plans to support asset strategy (e.g., first-in-human Phase I, proof-of-concept Phase I/II, entry registrational, biomarker qualification, clinical pharmacology studies).
- Liaises to define dose/schedule, indications, and patient selection; leads benefit/risk analysis.
Health Authority Interactions
- Contributes to Health Authority interactions/advisory boards as Early Clinical Development Physician; serves as Primary Clinical Representative in regulatory interactions.
- Authors/drafts clinical content for CSRs, regulatory reports, briefing books, and submission documents.
External Partnerships, Alliances, and Publications
- Establishes alliances with academic centers, cooperative groups, vendors, and government agencies; represents department in due diligence and partner alliance management.
- Demonstrates contributions to the field (e.g., publications, patents, keynote participation).
Reporting Relationship
- Reports to Executive Director, Early Clinical Development, Solid Tumors.
Qualifications
- MD or MD/PhD (or x-US equivalent) with clinical expertise in a therapeutic area (attending level or international equivalent).
- Subspecialty fellowship training in applicable therapeutic area preferred.
- 5+ years of relevant experience in discovery, translational and/or clinical research.
- Ability to communicate/present clearly in scientific/clinical settings.
- Expertise in scientific method (statistical design, analysis, interpretation).
- Knowledge of drug development process and clinical plan/protocol execution.
- Strong leadership and teamwork skills.
- Serves as a primary source of medical accountability and oversight for multiple clinical trials.
- Manages Phase I/II studies with demonstrated decision-making capabilities.
- Provides medical and scientific expertise to cross-functional BMS colleagues.
- Maintains matrix management responsibilities across internal and external networks.
Duties/Responsibilities
Medical Monitoring
- Acts as an independent Medical Monitor for clinical trials (Phase 1 through Proof-of-Concept), articulating clinical development strategy; analyzing/interpreting/acting on clinical trial data; serving as principal functional author for regulatory submissions, study reports, and publications.
- Provides oversight and medical accountability for multiple early development trials.
- Manages site interactions with Clinical Scientist(s) for medical questions and education, including safety management.
- Assesses key safety-related serious adverse events and oversees safety narratives.
- Collaborates with Study Delivery Team (SDT) and may support Development Team.
- Provides medical strategic oversight in protocol development (e.g., inclusion/exclusion; safety-related considerations) and supports study execution (site activation, enrollment status, adjudication of protocol violations/deviations).
- Fulfills GCP/compliance obligations and maintains required training.
- Defines and establishes relationships with key global Phase 1 Centers.
Clinical Development Expertise & Strategy
- Designs and develops clinical studies/research plans to support asset strategy (e.g., first-in-human Phase I, proof-of-concept Phase I/II, entry registrational, biomarker qualification, clinical pharmacology studies).
- Liaises to define dose/schedule, indications, and patient selection; leads benefit/risk analysis.
Health Authority Interactions
- Contributes to Health Authority interactions/advisory boards as Early Clinical Development Physician; serves as Primary Clinical Representative in regulatory interactions.
- Authors/drafts clinical content for CSRs, regulatory reports, briefing books, and submission documents.
External Partnerships, Alliances, and Publications
- Establishes alliances with academic centers, cooperative groups, vendors, and government agencies; represents department in due diligence and partner alliance management.
- Demonstrates contributions to the field (e.g., publications, patents, keynote participation).
Reporting Relationship
- Reports to Executive Director, Early Clinical Development, Solid Tumors.
Qualifications
- MD or MD/PhD (or x-US equivalent) with clinical expertise in a therapeutic area (attending level or international equivalent).
- Subspecialty fellowship training in applicable therapeutic area preferred.
- 5+ years of relevant experience in discovery, translational and/or clinical research.
- Ability to communicate/present clearly in scientific/clinical settings.
- Expertise in scientific method (statistical design, analysis, interpretation).
- Knowledge of drug development process and clinical plan/protocol execution.
- Strong leadership and teamwork skills.