Director, Global Clinical Physician (Cardiovascular)
Bristol Myers Squibb
August 19, 2026
Remote friendly (Cambridge, MA)
United States
Clinical Research and Development
Director, Global Clinical Physician – Cardiovascular
Position Responsibilities
- Serve as clinical/medical contact in diligence conversations with target company scientific/clinical contacts; partner with senior BD leadership.
- Identify/enact best practices; escalate judgment calls as appropriate; provide timely updates to management/governance stakeholders.
- Lead literature review and competitive landscape assessment; translate findings into asset valuation and trial design benchmarking recommendations.
- Lead clinical development plan (early to late development) and present recommendations to governance committees and development leadership.
- Lead assessment of trial design elements (endpoints, statistical assumptions, enrollment criteria, patient eligibility risk) and provide input on feasibility and valuation assumptions.
- Lead development of trial design/feasibility benchmarking materials (sample size, enrollment assumptions, country selection) and shape medical narrative supporting deal feasibility.
- Lead clinical/medical input to diligence packages, including safety risk assessment; present findings to BD leadership/governance committees.
- Collaborate cross-functionally with Biostatistics, Regulatory, Commercial, Medical Affairs, and Clinical Pharmacology.
- Serve as therapeutic area medical resource across cardiovascular areas (e.g., lipid management, coronary artery disease, stroke, heart failure) and provide portfolio/pipeline strategy input.
- Provide guidance to Clinical Scientists and junior team members.
- Identify/escalate medical/safety risks that may affect deal terms or timelines.
Qualifications & Required/Preferred Skills
- MD (or equivalent) required; board certification/eligibility in relevant specialty preferred; 6–8 years clinical and/or industry experience preferred.
- Advanced knowledge of GCP/ICH, drug development process, study design, statistics, and clinical operations.
- Advanced ability to interpret clinical/safety data for deal-specific medical risk assessments.
- Advanced medical writing skills for diligence memos, deal narratives, and governance presentations.
- Advanced planning/project management skills across multiple concurrent deals.
- Detail-oriented, medically/scientifically rigorous; advanced therapeutic-area knowledge.
- Experience with data monitoring committees, dose review teams, and independent response adjudication committees.
- Working knowledge of deal structuring and asset valuation frameworks (NPV/eNPV, PTRS) (BD/diligence a plus but not required).
- Strong independent judgment under time pressure; adaptable in ambiguity.
- Advanced Microsoft Word/Excel/PowerPoint and data review tools; comfortable presenting to non-clinical/executive audiences.
Position Responsibilities
- Serve as clinical/medical contact in diligence conversations with target company scientific/clinical contacts; partner with senior BD leadership.
- Identify/enact best practices; escalate judgment calls as appropriate; provide timely updates to management/governance stakeholders.
- Lead literature review and competitive landscape assessment; translate findings into asset valuation and trial design benchmarking recommendations.
- Lead clinical development plan (early to late development) and present recommendations to governance committees and development leadership.
- Lead assessment of trial design elements (endpoints, statistical assumptions, enrollment criteria, patient eligibility risk) and provide input on feasibility and valuation assumptions.
- Lead development of trial design/feasibility benchmarking materials (sample size, enrollment assumptions, country selection) and shape medical narrative supporting deal feasibility.
- Lead clinical/medical input to diligence packages, including safety risk assessment; present findings to BD leadership/governance committees.
- Collaborate cross-functionally with Biostatistics, Regulatory, Commercial, Medical Affairs, and Clinical Pharmacology.
- Serve as therapeutic area medical resource across cardiovascular areas (e.g., lipid management, coronary artery disease, stroke, heart failure) and provide portfolio/pipeline strategy input.
- Provide guidance to Clinical Scientists and junior team members.
- Identify/escalate medical/safety risks that may affect deal terms or timelines.
Qualifications & Required/Preferred Skills
- MD (or equivalent) required; board certification/eligibility in relevant specialty preferred; 6–8 years clinical and/or industry experience preferred.
- Advanced knowledge of GCP/ICH, drug development process, study design, statistics, and clinical operations.
- Advanced ability to interpret clinical/safety data for deal-specific medical risk assessments.
- Advanced medical writing skills for diligence memos, deal narratives, and governance presentations.
- Advanced planning/project management skills across multiple concurrent deals.
- Detail-oriented, medically/scientifically rigorous; advanced therapeutic-area knowledge.
- Experience with data monitoring committees, dose review teams, and independent response adjudication committees.
- Working knowledge of deal structuring and asset valuation frameworks (NPV/eNPV, PTRS) (BD/diligence a plus but not required).
- Strong independent judgment under time pressure; adaptable in ambiguity.
- Advanced Microsoft Word/Excel/PowerPoint and data review tools; comfortable presenting to non-clinical/executive audiences.