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Director, Exploratory Research

Rhythm Pharmaceuticals Inc.
August 12, 2026
Full-time
Remote friendly (Boston, MA)
Worldwide
Clinical Research and Development
Role: Lead exploratory research initiatives to deepen understanding of disease biology and inform pipeline development for rare neuroendocrine diseases. Responsibilities: design, oversee, and interpret mechanistic and translational in vitro and in vivo studies; identify and evaluate emerging scientific opportunities; develop innovative hypotheses, assays, and models; integrate multidisciplinary data to guide strategic decisions; manage external collaborations with CROs, academic partners, and experts; communicate findings to senior leadership and ensure scientific rigor in a fully outsourced research model. Requirements: PhD in neuroscience, endocrinology, pharmacology, or related field; 10+ years of relevant biotech or pharma R&D experience, including 5+ years leading independent research; expertise in neuroendocrine biology, metabolic or CNS-peripheral signaling pathways; proficiency in small molecule and peptide pharmacology; strong organizational, communication, and leadership skills. HighValue: rare neuroendocrine diseases, nonclinical pharmacology, exploratory biology, CRO-based research, development of novel models and assays, strategic scientific leadership. WorkSetup: hybrid Boston office; some travel likely.