Director, Drug Safety

Role: Lead pharmacovigilance for Nurix's targeted protein degradation therapies, focusing on patient safety, safety data analysis, and benefit–risk assessments. Responsibilities include medical safety leadership, aggregate safety data review for signal detection and evaluation, oversight of regulatory safety documentation (including DSURs, IND safety sections), and providing clinical input into trial protocols and safety strategies. The role also involves participating in safety governance, supporting regulatory interactions, and ensuring compliance with global pharmacovigilance standards. Requirements: MD, DO, PharmD, or equivalent with 5–10 years in pharma/biotech drug safety, preferably supporting early clinical development in small biotech settings. Expertise in aggregate safety analysis, signal detection, benefit–risk evaluation, and global safety regulations (ICH, FDA, EMA) is essential. Experience with safety surveillance tools, strong cross-functional leadership, and communication skills are required. High-value biopharma specifics: focus on clinical-stage therapies, early-stage development, safety signal detection, and regulatory reporting; based onsite in Brisbane, CA. Collaboration with clinical, regulatory, and medical affairs teams is integral.