Director, Cyber Architecture & Engineering
Alnylam Pharmaceuticals
September 02, 2026
Remote friendly (Cambridge, MA)
United States
IT
Responsibilities:
- Define and own Alnylam’s enterprise cybersecurity architecture and target state aligned to business growth, regulatory requirements, and risk appetite.
- Lead the design and evolution of a Zero Trust architecture (identity, least privilege, segmentation, continuous verification).
- Establish and maintain cyber reference architectures, design patterns, and standards across identity, cloud, applications, data, infrastructure, and endpoints.
- Serve as senior security architecture authority for major enterprise initiatives.
- Partner with IT and Expertise Areas to align cybersecurity architecture with broader technology strategy.
- Translate strategy into resilient, enterprise-grade security capabilities.
- Provide architectural input into vendor selection, platform strategy, and solution design.
- Establish governance for architecture reviews, risk-based exceptions, and technical debt remediation.
- Translate cybersecurity strategy into multi-year roadmaps with milestones, dependencies, and measurable outcomes.
- Define and track architecture-related metrics for risk reduction, consistency, and maturity.
- Lead, mentor, and grow security architects and engineers.
Qualifications:
- Bachelor’s in computer science, information security, engineering, or related field; Master’s or MBA preferred.
- 10+ years in cybersecurity/security architecture/enterprise technology design; 8+ years leadership experience.
- Certifications strongly preferred (CISSP, CCSP, SABSA, TOGAF, or equivalent).
- Expertise across IAM, cloud/hybrid, application/API security, network segmentation/Zero Trust, and data protection.
- Familiarity with NIST CSF, NIST 800-53, and Zero Trust concepts.
- Ability to influence senior stakeholders in complex/regulatory environments.
- Strong communication skills.
Benefits:
- Medical, dental, vision; life and disability insurance; lifestyle reimbursement; flexible spending/HSAs; 401(k) with generous match; paid time off, wellness days, holidays, and two recharge breaks; family resources and leave.
- Define and own Alnylam’s enterprise cybersecurity architecture and target state aligned to business growth, regulatory requirements, and risk appetite.
- Lead the design and evolution of a Zero Trust architecture (identity, least privilege, segmentation, continuous verification).
- Establish and maintain cyber reference architectures, design patterns, and standards across identity, cloud, applications, data, infrastructure, and endpoints.
- Serve as senior security architecture authority for major enterprise initiatives.
- Partner with IT and Expertise Areas to align cybersecurity architecture with broader technology strategy.
- Translate strategy into resilient, enterprise-grade security capabilities.
- Provide architectural input into vendor selection, platform strategy, and solution design.
- Establish governance for architecture reviews, risk-based exceptions, and technical debt remediation.
- Translate cybersecurity strategy into multi-year roadmaps with milestones, dependencies, and measurable outcomes.
- Define and track architecture-related metrics for risk reduction, consistency, and maturity.
- Lead, mentor, and grow security architects and engineers.
Qualifications:
- Bachelor’s in computer science, information security, engineering, or related field; Master’s or MBA preferred.
- 10+ years in cybersecurity/security architecture/enterprise technology design; 8+ years leadership experience.
- Certifications strongly preferred (CISSP, CCSP, SABSA, TOGAF, or equivalent).
- Expertise across IAM, cloud/hybrid, application/API security, network segmentation/Zero Trust, and data protection.
- Familiarity with NIST CSF, NIST 800-53, and Zero Trust concepts.
- Ability to influence senior stakeholders in complex/regulatory environments.
- Strong communication skills.
Benefits:
- Medical, dental, vision; life and disability insurance; lifestyle reimbursement; flexible spending/HSAs; 401(k) with generous match; paid time off, wellness days, holidays, and two recharge breaks; family resources and leave.