Director Commercial FP&A

Role Summary

Praxis Medicines is seeking a Commercial FP&A leader to serve as a strategic finance partner to the Commercial organization as we prepare for launch and scale toward a multi‑billion‑dollar revenue organization. This role will support near‑term launch readiness while also building the financial capabilities, discipline and insights required to operate at commercial scale over time. Location: remote with the flexibility to travel as needed. Sits within Finance but works in close, real‑time partnership with Commercial, CMC and other cross‑functional teams, embedding in ongoing commercial workstreams to enable forward‑looking decision‑making through continuous engagement rather than periodic reporting.

Responsibilities

• Act as the primary FP&A partner to Commercial leadership, supporting brand strategy, launch planning and revenue forecasting from pre-launch through scale.
• Perform revenue modeling, scenario and sensitivity analyses and key commercial assumptions as the business grows to multi‑billion‑dollar revenue levels.
• Partner closely with CMC and Supply Chain teams on inventory assumptions, demand planning and working capital considerations.
• Collaborate cross‑functionally on pricing, gross‑to‑net, market access and demand dynamics.
• Lead Commercial and CMC input into budgets, ongoing forecasts and long‑range plans.
• Evaluate investment decisions through ROI analysis and financial modeling to support prioritization and resource allocation.
• Develop executive‑ready materials that clearly communicate risks, opportunities and trade‑offs.
• Continuously improves forecasting tools, processes and analytical rigor to support a scaling commercial organization.

Qualifications

• 12–15+ years of experience in FP&A or strategic finance, with strong commercial exposure
• Biopharma experience required, including experience supporting a commercial‑stage company
• Experience supporting product launch and operating in a scaled commercial environment preferred
• Advanced financial modeling and analytical skills
• Proven ability to influence and partner with senior stakeholders across Finance, Commercial and CMC
• Strong business judgment and executive communication skills
• Comfortable operating in a fast‑paced, evolving environment with ambiguity

Additional Requirements

• The physical and mental requirements of our roles include regular use of a computer, devices or other office equipment, clear communication, and occasional movement. You’ll need comfort with screen work, basic hand coordination, and focus. Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.