Director, Commercial Distribution Operations
Ionis Pharmaceuticals, Inc.
September 25, 2026
Full-time
Remote friendly (Boston, MA)
Worldwide
Operations
Role: Director of Commercial Distribution Operations overseeing Ionis' product distribution and Order to Cash processes. Objectives: ensure efficient, compliant delivery of innovative RNA-based therapies globally; develop and execute distribution strategies; support ERP platform integration. Responsibilities: manage domestic 3PL partnerships, lead distribution operations, design and implement ERP system enhancements (SAP S4/Hana), ensure regulatory compliance, and oversee data analytics for supply chain metrics. Collaborate with cross-functional teams including Commercial, Quality, Regulatory, and Finance to optimize distribution and supply continuity. Lead a technical team responsible for product accessibility within channels, manage vendor relations, and oversee state licensing requirements. Requirements: bachelorβs degree in health sciences or business, with 15+ years in pharma/biotech supply chain or distribution roles, including product launch experience; strong understanding of US pharmaceutical distribution, regulatory standards, and ERP systems. Preferred: MBA or advanced degrees, experience with rare/ultra-orphan drugs, and specialty product launches. High-Value: focus on rare disease/ultra-orphan products, US or global markets, GxP compliance, and SAP S4/Hana platform expertise. Work setup: onsite/hybrid in Carlsbad, CA or Boston, MA, or remote with travel. The role demands proven leadership, strategic planning, collaboration skills, and technical proficiency in supply chain operations within the biopharma industry.