Director, Clinical Scientist - Immunology
AstraZeneca
September 19, 2026
Full-time
Remote friendly (Cambridge, MA)
Worldwide
Clinical Research and Development
Role: Director, Clinical Scientist in Neuroimmunology, leading study-level clinical science for cell and immunotherapies targeting neurological diseases like multiple sclerosis. Responsibilities: oversee day-to-day scientific activities, including document authoring, protocol development, medical and data review, safety surveillance, and external regulatory interactions; mentor junior scientists and collaborate with Study Physicians, Program Leads, and cross-functional teams. Requirements: PhD, PharmD, MD, or equivalent; 6+ years clinical development experience with hands-on trial execution, medical review, and safety data analysis; strong knowledge of GCP, regulatory standards, and trial methodology; experience in neurology, MS, or cell/gene therapies preferred. High-Value: involvement in early-phase (Phase 1/2), cell/gene therapy modalities, global regulatory compliance, and clinical operations; familiarity with clinical databases, programming, and CMC/biologics interfaces advantageous. Collaboration: partner closely with physicians, data teams, and external vendors, reporting to the Global Clinical Head. Work setup: not specified, with travel likely required. The role emphasizes scientific leadership, operational excellence, and strategic input within a R&D environment focused on innovative neuroimmunology therapeutics.