Director, Clinical Scientist

Role: The Director, Clinical Scientist leads clinical development efforts for Dyne’s neuromuscular disease programs, supporting strategy, trial design, and data interpretation. Responsibilities include serving as a scientific lead for clinical studies, collaborating across functions (Clinical Operations, Biostatistics, Regulatory, Medical Affairs), overseeing study execution, interpreting clinical and safety data, and contributing to regulatory submissions and scientific publications. The role involves mentoring team members, representing clinical insights internally and externally, and ensuring study quality and compliance. Qualifications: Advanced degree in life sciences, PhD/MD/PharmD preferred; 8+ years in clinical development, with experience supporting late-stage, global trials in rare neuromuscular diseases, particularly genetic medicines or oligonucleotide therapeutics. Requires strong knowledge of GxP, ICH, FDA/EMA regulations, and proficiency with clinical data systems. High-value specifics: focus on neuromuscular and genetic disorders, involvement in complex therapeutic modalities, late-phase clinical trial support, and collaboration with external investigators and vendors. The role demands excellent scientific judgment, communication skills, cross-functional influence, and approximately 20% domestic and international travel.