Director, Clinical Science (MD)

Role Summary

Director, Clinical Science (MD) at Corbus Pharmaceuticals. This senior role focuses on clinical development, scientific strategy, and medical affairs, providing leadership and cross-functional oversight of clinical studies and the scientific aspects of global trial delivery. The role supports planning, publication strategy, and safety analysis, and collaborates with external clinicians and internal teams to advance late-stage programs. Located in Norwood, Massachusetts (hybrid: 3 days onsite weekly).

Responsibilities

• Leads and/or participates in meetings and activities related to early development/Phase I studies, providing clinical science input and guidance; contributes to and reviews clinical protocols.
• Gathers, analyzes, and summarizes data to create the Clinical Development plan; may delegate research and analysis to others.
• Maintains scientific and clinical knowledge in assigned therapeutic areas and participates in competitive intelligence.
• Represents Clinical Development in collaboration with Research and Translational Sciences on biomarker strategy and pharmacological assessments; supports Clinical Development Plan Implementation.
• Reviews and/or writes clinical science documentation (e.g., protocol summaries, safety monitoring plans, investigator brochures).
• Supports completion and submission of regulatory filings and other regulatory documentation.
• Oversees review, analysis, and reporting of clinical data with biometrics and data management to enable decision making and regulatory filings.
• Collaborates on safety narratives and safety-related guidelines; acts as primary CD liaison for inquiries from clinical operations and CROs where assigned.
• Writes/edits abstracts, posters, and materials for scientific meetings; coordinates submissions to meetings and venues.
• Leads clinical study protocol development; translates strategy into executable protocols and documents.
• Keeps abreast of external environment to incorporate scientific innovations into trial development strategy.
• Evaluates innovative trial designs with Head of Operations and CMO.
• Co-leads cross-functional clinical trial working groups; drives delivery and issue resolution with Clinical Operations and external functions.
• Collaborates with Clinical Operations to plan site evaluation/initiation and maintains relationships with clinical sites globally.
• Identifies study/program-wide safety, efficacy, and PK/PD issues; develops strategic solutions and ensures issue resolution.
• Develops presentations with the CMO and communicates study results to internal colleagues and external audiences, including investigators and conference attendees.
• Contributes strategically to the overall clinical development pipeline and documentation strategy.

Qualifications

• MD or combined MD/PhD
• 5 years of clinical research experience in pharma/biotech or related settings; 10+ years of relevant clinical trial experience with at least 5 years in high-level pharma/biotech roles
• Ability to communicate complex scientific and medical information clearly and accurately
• Strong understanding of life sciences, medical terminology, and clinical trial processes (advanced degree typically required)
• Familiarity with regulatory agency requirements and processes for authoring submissions
• Ability to interpret and present complex scientific and statistical data