Director, Clinical Science

Role: Director, Clinical Science at Olema Oncology, focusing on ongoing clinical studies for breast cancer therapies. Responsibilities: collaborate across multidisciplinary teams to plan, conduct, and analyze clinical trials; author and review protocols, investigator's brochures, and regulatory documents; evaluate safety, pharmacology, and efficacy data; support publication efforts and scientific presentations; ensure adherence to GCP and regulatory standards; foster investigator relationships and facilitate trial operations. Requirements: PhD or PharmD preferred; minimum 8 years' oncology clinical development experience; deep knowledge of oncology trial design, drug development processes, and regulatory guidelines (FDA, EMA). High-value: Senior leadership role in late-stage (Phase 3) breast cancer programs, with emphasis on ER+/HER2- metastatic breast cancer; expertise in biologics or small molecules; experience with global regulatory and ethical standards; ability to manage complex data and support regulatory submissions. Work setup: based in San Francisco, CA or Cambridge, MA; up to 20% travel.