Director, Clinical Science
Janux Therapeutics
August 06, 2026
Remote friendly (San Diego County, CA)
United States
Clinical Research and Development
Essential Functions and Responsibilities:
- Support design and implementation of development strategies for programs entering the clinic.
- Collaborate with Clinical Operations to design and execute clinical trials; assist with protocols, ICFs/amendments, CRFs, CSRs, and Investigator Brochures.
- Aid in development of Data Review Plan and Data Review Strategy to ensure consistent protocol implementation.
- Perform clinical data review, identifying insights via patient-level review and trend analysis.
- Drive quality review with emphasis on subject safety/eligibility, data integrity, trend identification/remediation, and identification of AEs/SAEs for medical review.
- Support ad-hoc Regulatory activities (authoring/reviewing clinical portions of regulatory documents; posters, abstracts, manuscripts; meetings with regulators/consortia).
- Develop/deliver clinical presentation materials for internal and external meetings.
- Maintain scientific/clinical knowledge in assigned therapeutic and disease areas.
Education/Experience/Knowledge/Skills:
- BS in life sciences or related field; MS/PhD preferred.
- Minimum 8 years industry experience; 5+ years as a Clinical Scientist conducting clinical trials.
- Knowledge of oncology drug development, clinical trial processes, study design, statistics, and clinical operations.
- Skills in program-specific data review and trend analysis.
- Knowledge of data monitoring committees, dose review teams, and independent response adjudication.
- Knowledge of GCP and regulatory requirements; ability to critically evaluate data/literature.
- Ability to lead/work with cross-functional teams; strong project management.
Benefits (as stated): Annual bonus program; incentive stock option plan; 401k with flat non-elective employer contribution; medical/dental/vision; HSA/FSA and supplemental insurance; Unlimited PTO; generous holiday schedule; relocation assistance.
- Support design and implementation of development strategies for programs entering the clinic.
- Collaborate with Clinical Operations to design and execute clinical trials; assist with protocols, ICFs/amendments, CRFs, CSRs, and Investigator Brochures.
- Aid in development of Data Review Plan and Data Review Strategy to ensure consistent protocol implementation.
- Perform clinical data review, identifying insights via patient-level review and trend analysis.
- Drive quality review with emphasis on subject safety/eligibility, data integrity, trend identification/remediation, and identification of AEs/SAEs for medical review.
- Support ad-hoc Regulatory activities (authoring/reviewing clinical portions of regulatory documents; posters, abstracts, manuscripts; meetings with regulators/consortia).
- Develop/deliver clinical presentation materials for internal and external meetings.
- Maintain scientific/clinical knowledge in assigned therapeutic and disease areas.
Education/Experience/Knowledge/Skills:
- BS in life sciences or related field; MS/PhD preferred.
- Minimum 8 years industry experience; 5+ years as a Clinical Scientist conducting clinical trials.
- Knowledge of oncology drug development, clinical trial processes, study design, statistics, and clinical operations.
- Skills in program-specific data review and trend analysis.
- Knowledge of data monitoring committees, dose review teams, and independent response adjudication.
- Knowledge of GCP and regulatory requirements; ability to critically evaluate data/literature.
- Ability to lead/work with cross-functional teams; strong project management.
Benefits (as stated): Annual bonus program; incentive stock option plan; 401k with flat non-elective employer contribution; medical/dental/vision; HSA/FSA and supplemental insurance; Unlimited PTO; generous holiday schedule; relocation assistance.