Director, Clinical Research

Role: Lead clinical development for RNAi therapeutics in ATTR amyloidosis, providing strategic clinical leadership and overseeing trial conduct, safety, and regulatory approval processes. Responsibilities: collaborate across Research, Regulatory, Medical Affairs, and Clinical Operations; develop development strategies; ensure timely delivery of clinical documentation and regulatory submissions; act as a key external spokesperson. Requirements: MD or MD/PhD with strong research and clinical background; board certification or specialist training in cardiology, with expertise in heart failure and/or amyloidosis preferred; 3+ years industry or academic experience; comprehensive knowledge of clinical trial design, biostatistics, and regulatory practices; excellent communication and leadership skills in a matrix environment. High-Value: RNAi therapeutics, rare/genetic and common diseases, clinical development, regulatory strategy, experience in cardiology, amyloidosis, or heart failure. WorkSetup: hybrid (2 days onsite in Cambridge, MA or Philadelphia, PA); extensive cross-functional collaboration and external engagement.