Director, Clinical Data Management

Role: Lead clinical data management (CDM) for Entrada's diverse portfolio of genetic medicines targeting neuromuscular and inherited retinal diseases, including Duchenne muscular dystrophy and DM1. Responsibilities: develop and implement data standards, oversee CDM systems, lead vendor management, ensure data quality and compliance with GCP/ICH, and facilitate regulatory inspections. Manage internal teams and CRO partners, drive process improvements, and support trial delivery across multiple geographies. Requirements: BS in computer science or life sciences; 10+ years in industry CDM, with extensive CRO oversight, vendor management, and experience with Medidata RAVE, CDASH, SDTM, and GxP. Strong understanding of FDA/ICH GCP guidelines, clinical trial design, and data review tools like CluePoints or Spotfire. Experience in biologics, gene therapies, or oligonucleotide modalities preferred. Reports to the Head of Biometrics; remote US-based role with minimal travel to Boston headquarters. High-Value: Rare disease focus, genetic medicines, neuromuscular and retinal indications, multiple phase, regulatory compliance, clinical data systems innovation.