Director, Biostatistics
Tango Therapeutics
August 13, 2026
Remote friendly (Boston, MA)
United States
Clinical Research and Development
Your Role
- Serve as a biostatistics expert for Tango’s clinical programs.
- Provide strategic input to optimize trial designs in early phase dose escalation studies and late phase registrational studies.
- Collaborate with internal and external CRO teams to plan and execute statistical deliverables.
- Conduct statistical modeling to enable robust, efficient statistical designs and address statistical issues.
- Contribute to clinical protocol development (authoring/reviewing Statistics sections and applying statistical principles to other sections).
- Author/review statistical analysis plans; oversee development of tables, figures, and listings and associated deliverables.
- Review eCRF designs to ensure data collection meets statistical analysis requirements.
- Provide statistical input for clinical documents.
- Perform QC/QA of statistical deliverables, including validation of key analysis results.
- Perform ad hoc statistical analyses as needed.
- Contribute to clinical study reports (author statistical methods; interpret results).
- Support IND/NDA/MAA (or other regulatory submissions), including review of datasets, define files, reviewer’s guides, and related documents.
- Address statistical questions/comments from FDA and other regulatory agencies or IRBs/ECs.
- Support publications (manuscripts, posters, oral presentations).
- Lead biostatistics standardization and process improvement; define biostatistics templates and standards.
- Represent Tango on statistical issues in meetings with external parties.
- Support inspection readiness activities as needed.
- Develop and maintain advanced competencies in statistical methodology and trial designs (particularly oncology).
What You Bring (Qualifications)
- PhD in statistics (or related); or MS with appropriate relevant experience.
- At least 10 years’ pharmaceutical/biotech industry experience.
- Oncology experience required.
- Experience designing, analyzing, and reporting clinical trials.
- Experience with INDs/NDAs/MAAs or other regulatory submissions.
- In-depth knowledge of clinical trial statistical methods.
- Knowledge of FDA/EMA/ICH regulations and guidelines.
- Proficient in SAS and R.
- Ability to lead statistical efforts across multiple studies.
- Fluency in SDTM and ADaM data standards.
- Experience with outsourced statistical services via CROs.
- Ability to work independently and take initiative.
- Excellent written and oral communication.
Salary range
- $191,200—$286,800 USD
- Serve as a biostatistics expert for Tango’s clinical programs.
- Provide strategic input to optimize trial designs in early phase dose escalation studies and late phase registrational studies.
- Collaborate with internal and external CRO teams to plan and execute statistical deliverables.
- Conduct statistical modeling to enable robust, efficient statistical designs and address statistical issues.
- Contribute to clinical protocol development (authoring/reviewing Statistics sections and applying statistical principles to other sections).
- Author/review statistical analysis plans; oversee development of tables, figures, and listings and associated deliverables.
- Review eCRF designs to ensure data collection meets statistical analysis requirements.
- Provide statistical input for clinical documents.
- Perform QC/QA of statistical deliverables, including validation of key analysis results.
- Perform ad hoc statistical analyses as needed.
- Contribute to clinical study reports (author statistical methods; interpret results).
- Support IND/NDA/MAA (or other regulatory submissions), including review of datasets, define files, reviewer’s guides, and related documents.
- Address statistical questions/comments from FDA and other regulatory agencies or IRBs/ECs.
- Support publications (manuscripts, posters, oral presentations).
- Lead biostatistics standardization and process improvement; define biostatistics templates and standards.
- Represent Tango on statistical issues in meetings with external parties.
- Support inspection readiness activities as needed.
- Develop and maintain advanced competencies in statistical methodology and trial designs (particularly oncology).
What You Bring (Qualifications)
- PhD in statistics (or related); or MS with appropriate relevant experience.
- At least 10 years’ pharmaceutical/biotech industry experience.
- Oncology experience required.
- Experience designing, analyzing, and reporting clinical trials.
- Experience with INDs/NDAs/MAAs or other regulatory submissions.
- In-depth knowledge of clinical trial statistical methods.
- Knowledge of FDA/EMA/ICH regulations and guidelines.
- Proficient in SAS and R.
- Ability to lead statistical efforts across multiple studies.
- Fluency in SDTM and ADaM data standards.
- Experience with outsourced statistical services via CROs.
- Ability to work independently and take initiative.
- Excellent written and oral communication.
Salary range
- $191,200—$286,800 USD