Director - Application Site-Reliability Engineering

Role: Head of Application Reliability for clinical software at Caris Life Sciences, focusing on ensuring application stability, compliance, and operational excellence for their precision-oncology platform. Responsibilities include managing production support, incident response, and on-call rotation; establishing and maintaining SOX and FDA-compliant access controls; defining and tracking SLOs, error budgets, and operational metrics; leading incident management as incident commander; developing automation and runbooks; overseeing deployment processes and release governance; hiring and developing the Application Site Reliability Engineering (App-SRE) team; and maintaining application-layer observability. The role emphasizes automation-first operations, integrating AI tools, and ensuring compliance with regulatory standards, including FDA and SOX. Collaboration spans engineering, security, quality, and infrastructure teams, with high-level communication to leadership and audit bodies. The position is based in Irving, Texas (hybrid/on-site), with a minimum of three days on campus, and may require occasional travel. The candidate must have 10+ years in SRE, DevOps, or production operations, with at least 4 years in a leadership role; experience with incident management for critical systems under regulatory frameworks; and a strong background in automation and AI-assisted operational practices. Preferred background includes clinical diagnostics, laboratory systems, and cloud-native observability tools. The role serves as a senior escalation point, contributing technically while leading a team, with a focus on reducing operational toil through automation.