Dir/Senior Director, Toxicology & Preclinical Pharmacology

Role: Senior/Director level lead in preclinical pharmacology and toxicology for metabolic disease and obesity therapies, supporting peptide and small-molecule candidates from discovery through IND. Responsibilities: design, oversee, and interpret in vitro/in vivo GLP and non-GLP toxicology studies; serve as scientific lead for CRO interactions; integrate pharmacology, toxicokinetics, pathology, and biomarker data for development decisions; contribute to regulatory submissions (INDs, NDAs); collaborate with cross-functional teams for dose and risk assessments; mentor junior scientists and support strategic planning for combination therapies. Requirements: PhD, DVM, PharmD or equivalent in Pharmacology, Toxicology, or related field; 10+ years pharmaceutical/biotech experience, with expertise in metabolic pharmacology, GLP toxicology, and translational science; experience supporting IND-enabling programs; familiarity with regulatory guidelines and peptide/small molecule development. High-Value: metabolic pathways (GLP-1, GIP, amylin), obesity therapeutics, GLP-compliant toxicology, early clinical development support. WorkSetup: hybrid/remote/onsite, no travel specified.