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Corporate Accounting Manager

Disc Medicine
4 months ago
Remote friendly (Watertown, MA)
United States
Corporate Functions
Responsibilities:
- Lead the monthly, quarterly, and annual close processes, ensuring timely and accurate financial reporting.
- Apply U.S. GAAP and maintain strong internal control structure; challenge current processes/procedures as a trusted business partner.
- Prepare/review complex journal entries, account reconciliations, and variance analyses to support month-end, quarter-end, and year-end closes and accurate U.S. GAAP reporting.
- Lead the monthly accrual process across research, clinical operations, CMC, G&A, and commercial functions to ensure expense recognition reflects operational activity.
- Partner with FP&A and cross-functional teams (Clinical Operations, CMC, etc.) to validate spend and inform accrual estimates.
- Develop, maintain, and review clinical accrual models for multiple programs/phases to ensure accurate recognition of costs incurred but not yet invoiced.
- Serve as a key liaison for interim and year-end internal and external integrated audits; execute, document, and test internal controls; prepare audit schedules and supporting materials.
- Analyze and explain variances between actual results, forecasts, and budgets to management and external auditors.
- Other duties as assigned.

Requirements:
- Bachelor’s degree in accounting, finance, or related field.
- 5+ years of progressive accounting experience, typically including public accounting and biotechnology/life sciences industry experience.
- Strong knowledge of U.S. GAAP.
- CPA preferred.
- Excellent communication and interpersonal skills; able to collaborate across functional teams.
- Ability to work in a dynamic, fast-paced, rapidly changing environment and manage multiple priorities.
- ERP experience such as NetSuite and Coupa (preferred); advanced Excel skills required.
- Minimum 3 years of experience with internal controls under Section 404(b) of the Sarbanes-Oxley Act (SOX); working knowledge of drug development processes in biotech/pharmaceutical, including clinical trial accruals.