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Computational Infrastructure Scientist – Biological Data Systems

Eli Lilly and Company
On-site
Indianapolis, IN
$151,500 - $244,200 USD yearly
IT

Role Summary

We are seeking a Computational Infrastructure Scientist to help build and extend the data systems that power large-scale biological and genetic research — the foundations of modern biology and precision medicine. This is a scientific engineering position, ideal for a PhD-level scientist who bridges biology, computation, and informatics. The successful candidate will have a deep understanding of the complexity and diversity of biological and genetic data, and a passion for designing robust, reusable infrastructure that makes this data usable, reproducible, and scalable across research and discovery pipelines.

Responsibilities

  • Strategize and implement scientific data processing workflows that transform complex biological datasets into actionable insights.
  • Design and develop innovative algorithms and ETL systems to address emerging challenges in biological and drug discovery data integration.
  • Collaborate cross-functionally with domain scientists and engineers to translate biological questions into computational frameworks.
  • Contribute to the long-term architecture and evolution of the data platform, ensuring scalability, transparency, and reproducibility.
  • Develop cloud-based workflows and APIs that enable efficient access and analysis across diverse biological datasets.
  • Document and share design decisions to promote reuse and institutional knowledge.

Qualifications

  • Required: PhD in Computational Biology, Chemistry, Bioinformatics, or a related scientific field.

Additional Skills/Preferences

  • Preferred: Strong programming experience in Python and strong familiarity with R.
  • Preferred: Experience working in Linux environments.
  • Preferred: Knowledge of biological databases, ontologies, and metadata systems.
  • Preferred: Knowledge in PostgreSQL databases
  • Preferred: Proficiency in Linux environments and Git (required).
  • Preferred: Exposure to cloud platforms (e.g., AWS S3, EC2, or equivalent).
  • Preferred: Experience working with workflow execution environments including NextFlow
  • Preferred: Experience developing data-driven decision support applications including data and visual analytical tools
  • Preferred: Exposure to Docker or containerized environments.
  • Preferred: Strong communication skills and the ability to work independently on open-ended technical problems.
  • Preferred: Understanding of web design and API is a plus.
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